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Showing result 1 - 5 of 615 swedish dissertations matching the above criteria.

  2. 1. Chrohn's disease : aspects of epidemiology, clinical course, and faecal calprotectin

    Author : Yaroslava Zhulina; Jonas Halfvarson; Curt Tysk; Hans Strid; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Crohn’s disease; epidemiology; faecal calprotectin; Medicine; Medicin;

    Abstract : The overall aim of this thesis was to study epidemiological and clinical changes in the natural history of Crohn’s disease, its phenotype, the need for surgery and pharmacological therapy over time, as well as the role of faecal calprotectin as a biomarker of pathophysiology and disease course.An increased incidence and prevalence of Crohn’s disease was seen in the period 1963-2010. READ MORE

  4. 2. Crohn's disease : Studies on epidemiology, twins, aetiological factors and clinical course with special reference to smoking

    Author : Eva Lindberg; Linköpings universitet; []
    Keywords : Crohn s disease; epidemiology; incidence; prevalence; smoking; genetics; twins; dietary antigens; yeast; Saccharomyces cerevisiae; mannan; gliadin; betalactoglobulin; ovalbuntin; MEDICINE; MEDICIN;

    Abstract : In an epidemiological study of the incidence of Crohn's disease in Orebro county during the 25-year period 1963-1987, the mean annual incidence was 6.1/105 inhabitants. During the first five year period the mean incidence was 4.3 but during the following four quinquennia the incidence was stable at around 6. READ MORE

  5. 3. Autoantibodies and genetic variation in rheumatoid arthritis : aspects on susceptibility and disease course

    Author : Alf Kastbom; Thomas Skogh; Peter Söderkvist; Alex Karlsson-Parra; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; autoantibodies; single-nucleotide polymorphisms; disease course; Rheumatology; Reumatologi;

    Abstract : Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and subsequent destruction of synovial joints. Although its causes remain largely unknown, a substantial genetic contribution is known to exist. READ MORE

  6. 4. Epidemiological and therapeutic aspects of Inflammatory Bowel Disease

    Author : Carl Eriksson; Jonas Halfvarson; Scott Montgomery; Flemming Bendtsen; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammatory bowel disease; ulcerative colitis; Crohn’s disease; cohort study; population-based; colectomy; disease course; anaemia; azathioprine; 6-mercaptopurine; vedolizumab;

    Abstract : Introduction: The two main forms of inflammatory bowel disease (IBD) are Crohn’s disease and ulcerative colitis. These are chronic inflammatory disorders, mainly affecting the gastrointestinal tract. READ MORE

  7. 5. Hyperthyroidism : a chronic disease?

    Author : Gabriel Sjölin; Göran Wallin; Mikael Lantz; Laszlo Hegedus; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hyperthyroidism; Graves’ disease; toxic nodular goitre; longterm follow-up; Quality of Life; radioactivated iodine; antithyroid drugs; thyroidectomy; index patient;

    Abstract : During 2003-2005, approximately 3,000 de novo hyperthyroid patients were collected in Sweden and became one of the world's largest hyperthyroidism studies. This dissertation shows that many people diagnosed with hyperthyroidism live with its impacts even after excess of thyroid hormone has ended. READ MORE