Search for dissertations about: "disordered structure"

Showing result 11 - 15 of 159 swedish dissertations containing the words disordered structure.

  2. 11. Evolution and Binding Mechanisms of Intrinsically Disordered Proteins

    Author : Elin Karlsson; Per Jemth; Kaare Teilum; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Intrinsically disordered proteins; Protein evolution; Binding kinetics; Binding mechanisms; Biophysical characterisation; Medicinsk biokemi; Medical Biochemistry;

    Abstract : Intrinsically disordered proteins (IDPs) make up a considerable fraction of the proteome in eukaryotic organisms. These proteins often act as hubs in interaction networks, harbouring multiple interaction with other proteins, and thus evolution has to walk a tightrope to accommodate new interactions while maintaining the previously established interactions. READ MORE

  4. 12. Push the limitations of crystal structure determination by 3D electron diffraction : From inorganic porous materials to biomolecules

    Author : Jingjing Zhao; Xiaodong Zou; Hongyi Xu; Tim Grüne; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; electron crystallography; 3D electron diffraction; cryo-EM specimen preparation; structure determination; porous materials; biomolecules; fysikalisk kemi; Physical Chemistry;

    Abstract : Structure elucidation is fundamental to understanding the chemical and physical properties of a material. Three-dimensional electron diffraction (3D ED) has shown great power for structure determination of nanometer- or submicrometer-sized crystals that are either too small or too complex for X-ray diffraction. READ MORE

  5. 13. A journey towards complete structure determination of zeolites by electron crystallography methods

    Author : Elina Kapaca; Xiaodong Zou; Philippe Boullay; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Electron crystallography; Zeolites; Structure determination; Rotation electron diffraction; Continuous rotation electron diffraction; Disorder; Inorganic Chemistry; oorganisk kemi;

    Abstract : Electron crystallography has recently become very successful for structural studies of materials with sub-micrometer sized crystals. In this thesis two major techniques have been applied for structure elucidation – 3-dimensional electron diffraction (3D ED) and high-resolution transmission electron microscopy (HRTEM) imaging. READ MORE

  6. 14. An evolutionary basis for protein design and structure prediction

    Author : Christoffer Norn; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein evolution; Biophysics; Protein design; Protein structure prediction;

    Abstract : The sequence diversity of protein families is a result of the biophysical selection pressures that shaped their evolutionary history. Among the dominant pressures is selection for protein thermostability, which in itself is an attractive target in protein engineering because of its importance for various biopharmaceutical properties, the performance of industrial enzymes, and the ability to design new protein functions. READ MORE

  7. 15. Coarse-grained and atomistic modelling of phosphorylated intrinsically disordered proteins

    Author : Ellen Rieloff; Beräkningskemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; intrinsically disordered proteins; phosphorylation; simulations; Monte Carlo; molecular dynamics; coarse-graining; atomistic; statherin; small-angle X-ray scattering; circular dichroism;

    Abstract : Intrinsically disordered proteins (IDPs) are involved in many biological processes such as signalling, regulation and recognition. One of the main questions regarding IDPs is how sequence, structure and function are related. READ MORE