Search for dissertations about: "dissection"
Showing result 31 - 35 of 178 swedish dissertations containing the word dissection.
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31. Molecular dissection of pathways regulating glucose and lipid metabolism using siRNA
Abstract : Type 2 diabetes is a complex chronic disease that is associated with skeletal muscle insulin resistance. The aim of this thesis is to investigate pathways regulating glucose and lipid metabolism in human skeletal muscle. Whole body metabolism differs between men and women. READ MORE
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32. Population-based analyses of incidence, prognostic determinants and outcome of aortic dissection
Abstract : Background: Aortic dissection (AD) is a potentially life-threatening disease caused by a tear in the innermost layer of the aortic wall, the intima, resulting in blood flow between the layers of the aortic vessel wall. Main risk factors are hypertension, male sex and smoking. READ MORE
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33. A Proteomic Dissection of Breast Cancer - Via Cells and Organelles to Pathways
Abstract : Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in females worldwide. Breast tumours are extremely heterogeneous, and each patient’s disease has different causes, prognosis and appropriate treatments associated with it. READ MORE
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34. Genetic and molecular dissection of hemolymph coagulation and melanization in Drosophila melanogaster
Abstract : Injury to epithelial barriers puts metazoans at risk of loss of body fluid and contamination of their body by foreign particles. This risk is even exacerbated in insects, which have an open circulatory system and as a result, quickly need to seal wounds in order to keep a fairly constant internal milieu. READ MORE
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35. Molecular dissection of Bruton’s tyrosine kinase signaling in hematopoietic cells using RNAi
Abstract : RNA mediated gene silencing, RNA interference (RNAi), has recently been identified in mammalians. This thesis describes the utilization and development of RNAi based tools for signal transduction research. The effects of Bruton s tyrosine kinase (Btk) down-regulation with RNAi have been studied with gene expression profiling in hematopoietic cells. READ MORE