Search for dissertations about: "dissertation on acute pancreatitis"

Showing result 1 - 5 of 7 swedish dissertations containing the words dissertation on acute pancreatitis.

  2. 1. Acute Pancreatitis. Studies on smoking and protease activation

    Author : Björn Lindkvist; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; trypsinogen; Acute pancreatitis; trypsinogen activation peptide cathepsin B; incidence; smoking; nicotine; traumatologi; ortopedi; Kirurgi; traumatology; Surgery; orthopaedics; Gastroenterologi; Public health; epidemiology; Folkhälsa; epidemiologi; Gastro-enterology;

    Abstract : Background and aims: Activation of pancreatic proteases is considered to be a crucial event in the early phase of acute pancreatitis but the cause of this activation is not known. Most cases of acute pancreatitis can be attributed to either gallstone disease or alcohol abuse. However, little is known about other risk factors. READ MORE

  4. 2. On the Mechanism of Neutrophil Extracellular Traps in Acute Pancreatitis

    Author : Raed Madhi; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute pancreatitis; chemokines; neutrophil recruitment; PAD4; c-Abl kinase; NETs; NET-MPs complexes;

    Abstract : .... READ MORE

  5. 3. Acute pancreatitis, from local defense to remote organ injury

    Author : Hamid Akbarshahi; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute pancreatitis; heparan sulfate; damage associated molecular patterns; toll-like receptor4; MyD88; IRF-3; acute lung injury; macrophages; transforming growth factor-beta; Smad;

    Abstract : Acute pancreatitis (AP) is an inflammatory disease of the pancreas. Acute abdominal pain is the most common symptom. Pancreatic injury is mild in 80% of patients, who recover without complications. The remaining patients have a severe disease with local and systemic complications such as acute lung injury (ALI). READ MORE

  6. 4. Protease Activation and Inflammation in Acute Pancreatitis

    Author : Sara Regnér; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prediction of severity; CAPAP; proCAP; aCAP; Acute pancreatitis; MCP-1; Carboxypeptidase B; fibrinolysis;

    Abstract : Approximately 10—20 % of patients with acute pancreatitis (AP) develop a severe disease with high mortality and morbidity. Activation of pancreatic proteases, the inflammatory response and impaired pancreatic circulation are pathophysiological events that are important in order for the disease to develop. READ MORE

  7. 5. INITIATION OF EXPERIMENTAL ACUTE PANCREATITIS AND MODULATION OF INFLAMMATORY RESPONSE

    Author : Jakob B Axelsson; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nuclear factor kappa B; neutrophils; monocytes; acute pancreatitis; ductal cells; active site-inhibited factor seven; heparan sulfate; lipopolysaccharide; innate immune response;

    Abstract : Heparan sulfate (HS), a substance common in the extracellular matrix on epithelial cells is present in the pancreas, lining the duct lumen. During pathological conditions, we propose that it can be shed from the ECM and bind to receptors on the cell surface, thus triggering an inflammatory response, which if excessive can cause acute pancreatitis (AP). READ MORE