Search for dissertations about: "dissertation on pharmaceutical"

Showing result 1 - 5 of 722 swedish dissertations containing the words dissertation on pharmaceutical.

  1. 1. Pharmaceutical Nanocomposites Structure–Mobility–Functionality Relationships in the Amorphous State

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Joel Hellrup; Uppsala universitet.; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; amorphous; pharmaceutical composites; solid state; structure; molecular mobility; spray-drying; freeze-drying; moisture sorption; physical stability; compression; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : Amorphous materials are found in pharmaceutical formulations both as excipients and active ingredients. Indeed, these formulations are becoming an essential strategy for incorporating drugs into well-performing solid dosage forms. READ MORE

  2. 2. Cytochrome P450 Enzymes in Bile Acid Biosynthesis and Fatty Acid Metabolism Studies on Members of the Porcine CYP4A and CYP8B Subfamilies

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Kerstin Lundell; Uppsala universitet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biochemistry; cytochrome P450; bile acids; fatty acids; CYP4A; CYP8B; genome; porcine; hyocholic acid; Farmaceutisk biokemi; PHARMACY Pharmaceutical biochemistry; FARMACI Farmaceutisk biokemi; farmaceutisk biokemi; Pharmaceutical Biochemistry;

    Abstract : The present investigation is devoted to studies on porcine members of the cytochrome P450 4A (CYP4A) and CYP8B1 subfamilies, which are involved in bile acid biosynthesis and fatty acid metabolism. Hyocholic acid is considered to fulfil the requirements for trihydroxy bile acids in the domestic pig (Sus scrofa) in the absence of cholic acid. READ MORE

  3. 3. Growth hormone in the brain Focus on cognitive function

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Erika Brolin; Uppsala universitet.; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth hormone; central nervous system; cognition; morphine; gamma-hydroxybutyrate; diabetes; Barnes maze; Morris water maze; mice; rats; Pharmaceutical Science; Farmaceutisk vetenskap;

    Abstract : Cognitive impairments are an increasing health problem worldwide. In the developed countries, the average life expectancy has dramatically increased over the last decades, and with an elderly population more cases of cognitive impairments appear. READ MORE

  4. 4. Pharmaceutical binders and their function in directly compressed tablets Mechanistic studies on the effect of dry binders on mechanical strength, pore structure and disintegration of tablets

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Sofia Mattsson; Uppsala universitet.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; Compaction; tablet; binder; pore structure; disintegration; FARMACI; PHARMACY; FARMACI; farmaceutisk farmakologi; Pharmaceutical Pharmacology;

    Abstract : In this thesis, the strength-enhancing mechanisms of dry binders in direct compression were studied. The systems investigated were binary mixtures containing various compounds and binders. Among the binders used were a series of different molecular weights of polyethylene glycol. READ MORE

  5. 5. Enzymatic Regulation of Steroidogenesis and Nuclear Receptor Activation Special Focus on Vitamin D and Sex Hormones

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Johan Lundqvist; Uppsala universitet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adrenal steroidogenesis; CYP7B1; vitamin D; calcitriol; enzymatic regulation; transcriptional regulation; CYP21A2; aromatase; sex hormone; estrogen; androgen; nuclear receptor; PHARMACY Pharmaceutical biochemistry; FARMACI Farmaceutisk biokemi; Farmaceutisk biokemi; Pharmaceutical Biochemistry;

    Abstract : Enzyme-catalyzed reactions are important to regulate steroidogenesis and nuclear receptor activation. The present investigation examines the role of steroid metabolism catalyzed by CYP7B1 for regulation of hormone receptor activation and the effects of vitamin D on enzymatic regulation of steroidogenesis. READ MORE