Search for dissertations about: "dissertation topics in biochemistry"

Showing result 1 - 5 of 11 swedish dissertations containing the words dissertation topics in biochemistry.

  1. 1. Physiology of Saccharomyces cerevisiae Producing Recombinant Insulin in Continuous Culture

    Author : Ali Kazemi Seresht; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; unfolded protein response; Keywords: heterologous protein production; prolonged chemostat; transcriptome; insulin analogue precursor; metabolic adaptation; URA3d; plasmid copy number; promoter truncation; high cell density cultivation; TPI1;

    Abstract : The yeast Saccharomyces cerevisiae has widely been used as a host for the production of heterologous proteins. High-level production of heterologous proteins is likely to impose a metabolic burden on the host cell and can thus affect various aspects of cellular physiology. READ MORE

  2. 2. Inference of Hierarchical Structure in Complex Systems

    Author : Olof Görnerup; [2008]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Protein evolution; Substitution groups; Modularity; Hierarchical dynamics; RNA world; Genetic code; Aggregation; Primordial evolution; Molecular evolution; Model reduction; Self-organization; Lumping; Emergence; Coarse graining;

    Abstract : Hierarchical organization is a central property of complex systems. It is even argued that a system is required to be hierarchical in order to evolve complexity within reasonable time. A hierarchy of a system is defined as the set of self-contained levels at which the system operates and can be described on. READ MORE

  3. 3. Creating cell microenvironments in vitro

    Author : Patric Wallin; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cell migration; lipid bilayers; cell differentiation; liquid handling; surface functionalization; Microfluidics; chemotractant gradients; mammalian cell culture; cell microenvironments; in vitro screening assay;

    Abstract : Stem cells have a great potential to bring about advancements in fields like developmental biology, drug discovery, cancer biology and tissue engineering. In order to be able to use stem cells to their full potential, it is important to have control over their behavior. READ MORE

  4. 4. Chemical biology and digital image processing to unravel complex molecular mechanisms in Arabidopsis

    Author : Thomas Vain; Sveriges lantbruksuniversitet.; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The sessile life of plant directed their evolution toward multiple adaptive strategies. Rapid protein turn over has been described to be a key regulatory mechanism for plant adaptation. Ubiquitin-modified proteins are targeted for degradation by the 26S-proteasome. READ MORE

  5. 5. On the molecular mechanisms of the amyloid β-peptide aggregation

    University dissertation from Lund University, Faculty of Science, Department of Chemistry

    Author : Kalyani Sanagavarapu; Lund University.; Lunds universitet.; [2019-01]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein aggregation; amyloid β-peptide; aggregation kinetics; aggregation mechanism N-terminus; mutations; variants; sequence determinants; ; cross-seeding;

    Abstract : The pathogenesis of Alzheimer’s disease is widely believed to be due to production and deposition of the amyloid β-peptide. Several variants of the Aβ peptide are known to exist in in vivo. Variations include mutations or additional functional groups attached to residue side chains and may affect the aggregation process. READ MORE