Search for dissertations about: "distal colon"

Showing result 1 - 5 of 30 swedish dissertations containing the words distal colon.

  2. 1. HER3 expression and prognosis in colon and rectal cancer

    Author : Frida Lédel; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Colorectal cancer;

    Abstract : In Sweden, about 6000 patients get a colorectal cancer diagnosis annually. Advances in management of both colon and rectal cancer have reduced mortality even though the incidences are increasing. READ MORE

  4. 2. On Lactobacillus plantarum 299v, bacterial translocation and intestinal permeability

    Author : Peter Mangell; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacterial translocation; permeability; intestinal microflora; Kirurgi; orthopaedics; P-selectin; ortopedi; traumatologi; leukocyte recruitment; Lactobacillus plantarum 299v; traumatology; Surgery; colon resection;

    Abstract : The gastrointestinal tract harbours a huge load of bacteria which exerts important biological functions to maintain health. In certain conditions the relation between commensal bacteria and pathogens may be set off balance, with an increase in number of pathogens and risk of bacterial translocation (BT). READ MORE

  5. 3. Mucus associated proteins and their functional role in the distal intestine

    Author : Joakim H. Bergström; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intestine; mucus; bacteria; MUC2; AGR2; FCGBP; ZG16;

    Abstract : The mammalian intestine, especially the large intestine, harbors complex societies of beneficial bacteria coexisting with the host. This is a mutualistic relationship, where the host provides nutrients and a favorable environment while the bacteria in return ferment indigestible polysaccharides to short chain fatty acids. READ MORE

  6. 4. Neuromuscular function in the normal and inflamed colon. An experimental study in rat

    Author : Lars Börjesson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ATP; dextran sulphate sodium; DMPP; enteric nervous system; McN-A-343; nitric oxide; non-adrenergic; rat; second messenger; smooth muscle; VIP;

    Abstract : Neuromuscular function of the longitudinal muscle layer of distal colon was investigated in segments from normal rats and from rats with colitis induced by dextran sulphate sodium (DSS) at 3% for 3 or 7 days or 5% for 7 days. The study was performed in vitro, on spontaneous tone, or after precontraction. READ MORE

  7. 5. Colon cancer specific cytochrome P450 2W1 : polymorphism, membrane topology and endogenous roles in development

    Author : Jia Guo; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cytochrome P450 2W1 (CYP2W1) belongs to a family of drug metabolizing monooxygenases with an unidentified yet endogenous function. CYP2W1 expression pattern has characteristic features of oncofetal genes. Previous studies have shown significant levels of CYP2W1 protein in 30% of human colon cancers and in 50% of corresponding liver metastases. READ MORE