Search for dissertations about: "distribution of fitness effects"

Showing result 1 - 5 of 25 swedish dissertations containing the words distribution of fitness effects.

2. 1. Finding fitness : empirical and theoretical explorations of inferring fitness effects from population-level SNP data

   Author : Bea Angelica Andersson; Xiao-Ru Wang; Åke Brännström; Tanja Slotte; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; distribution of fitness effects; site frequency spectra; missing data filtering; downsampling; imputation; sample size; population structure; inbreeding; selfing; homozygosity; Arabidopsis; Pinus; DFE-alpha; SLiM; population genomics; adaptation; biology; biologi; evolutionär genetik; evolutionary genetics; populationsbiologi; Population Biology; molekylärbiologi; Molecular Biology; Genetics; genetik;

   Abstract : The distribution of fitness effects (DFE) describes the likelihood that a new mutation has a specific effect on the fitness of an individual in a given population. The shape of the DFE is a result of several factors such as population size, mating system and selective environment, and can in turn influence the evolutionary potential of a species. READ MORE

4. 2. Rates and patterns of molecular evolution in avian genomes

   Author : Paulina Bolívar; Hans Ellegren; Carina F. Mugal; Mikkel Heide Schierup; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Molecular evolution; recombination; GC-biased gene conversion; Hill-Robertson interference; effective population size; dN dS; distribution of fitness effects; avian genomes; collared flycatcher; sex chromosomes; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

   Abstract : Evolution is the change in inherited characteristics of a population through subsequent generations. The interplay of several evolutionary mechanisms determines the rate at which this change occurs. READ MORE

5. 3. Interaction of cyclotides and bacteria : A study of the cyclotide action and the bacterial reaction

   Author : Sohaib Zafar Malik; Ulf Göransson; Dan Andersson; William Shafer; Uppsala universitet; []
   Keywords : Cyclotides; cycloviolacin O2; cycloviolacin O3; cycloviolacin O19; antimicrobial peptide resistance; Salmonella enterica; Eschericia coli; Viola odorata; Farmakognosi; Pharmacognosy;

   Abstract : The growing problem of antibiotic resistance and the lack of promising prospective antibiotics have forced us to search for new classes of antibiotics. Among the candidates to develop into future antibacterials are antimicrobial peptides (AMPs). READ MORE

6. 4. Genetic and Ecological Consequences of Fish Releases : With Focus on Supportive Breeding of Brown Trout Salmo trutta and Translocation of European Eel Anguilla anguilla

   Author : Johan Dannewitz; Jacob Höglund; Erik Petersson; Ian Fleming; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biology; conservation; fishery management; panmixia; genetic variation; effective population size; hatchery selection; Biologi; Biology; Biologi;

   Abstract : Although the practice of releasing fish into the wild is common in the management and conservation of fish populations, the success of release programmes and the potential harmful genetic and ecological effects that may follow are rarely considered. This thesis focuses on genetic and ecological consequences of fish releases, exemplified by supportive breeding of brown trout (Salmo trutta) and translocation of European eel (Anguilla anguilla). READ MORE

7. 5. Evolutionary Dynamics of Mutation and Gene Transfer in Bacteria

   Author : Peter A Lind; Dan I Andersson; J. Arjan G. M. de Visser; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; fitness cost; bacterial evolution; gene amplification; mutational biases; GC content; synonymous substitutions; horizontal gene transfer; experimental evolution; Bacteriology; Bakteriologi; Microbiology; Mikrobiologi; Genetics; Genetik; Biology; Biologi; Mikrobiologi; Microbiology;

   Abstract : The study of bacterial evolution is fundamental for addressing current problems of antibiotic resistance and emerging infectious diseases and lays a solid foundation for successful and rational design in biotechnology and synthetic biology. The main aim of this thesis is to test evolutionary hypotheses, largely based on theoretical considerations and sequence analysis, by designing scenarios in a laboratory setting to obtain experimental data. READ MORE