Search for dissertations about: "dm"

Showing result 1 - 5 of 179 swedish dissertations containing the word dm.

  1. 1. Analysis of inherited and somatic variants to decipher canine complex traits

    Author : Kate Megquier; Kerstin Lindblad-Toh; Ingegerd Elvers; David Sargan; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; dog; genetics; GWAS; exome; cancer; DM;

    Abstract : This thesis presents several investigations of the dog as a model for complex diseases, focusing on cancers and the effect of genetic risk factors on clinical presentation.In Papers I and II, we performed genome-wide association studies (GWAS) to identify germline risk factors predisposing US golden retrievers to hemangiosarcoma (HSA) and B-cell lymphoma (BLSA). READ MORE

  2. 2. Evaluation of image quality and diagnostic accuracy in breast tomosynthesis. Comparison with digital mammography and estimates of radiation risk

    Author : Tony Svahn; Malmö Medicinsk strålningsfysik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diagnostic accuracy; breast tomosynthesis BT ; digital mammography DM ; average glandular dose AGD ; receiver operating characteristics ROC ; risk assessment; search-model SM ; proper ROC PROPROC ;

    Abstract : Recent advances in the digital detector technology have paved the way for modalities such as two-dimensional digital mammography (DM) and three-dimensional breast tomosynthesis (BT). In this work, experimental studies were conducted to investigate the influence of reducing the average glandular dose (AGD) on detection of simulated lesions in DM and to compare the diagnostic accuracy of BT and DM. READ MORE

  3. 3. Evaluation of the deoxyribonucleoside kinase of Drosophila Melanogaster (Dm-dNK) as a suicide gene for treatment of solid tumors

    Author : Xinyu Zheng; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : Nucleoside kinases from several species are investigated as "suicide genes" for treatment of malignant tumors. The transfer of the gene encoding herpes simplex virus type-1 thymidine kinase (HSV-1 TK) into malignant cells and subsequent treatment with ganciclovir is one of the most commonly studied strategies of suicide gene therapy. READ MORE

  4. 4. Designing Self-Adaptive Software Systems with Reuse

    Author : Nadeem Abbas; Jesper Andersson; Linnéuniversitetet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; Variability; Uncertainty; Self-Adaptation; Software Reuse; Software Design; Methodology; Domain Engineering.; Computer Science; Datavetenskap; Data- och informationsvetenskap; Computer and Information Sciences Computer Science; Software Technology; Programvaruteknik;

    Abstract : Modern software systems are increasingly more connected, pervasive, and dynamic, as such, they are subject to more runtime variations than legacy systems. Runtime variations affect system properties, such as performance and availability. The variations are difficult to anticipate and thus mitigate in the system design. READ MORE

  5. 5. Engineering Decentralized Learning in Self-Adaptive Systems

    Author : Mirko D'Angelo; Mauro Caporuscio; Jesper Andersson; Lionel Seinturier; Linnéuniversitetet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Self-adaptive systems; Service assembly; Resiliency; Decentralized control architecture; Machine learning; Reasoning framework; Computer Science; Datavetenskap;

    Abstract : Future computing environments are envisioned to be populated by myriads of pervasive real-world things, which collaborate to offer boundless opportunities to industry and society -- e.g., smart cities, and intelligent transportation systems. READ MORE