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Showing result 1 - 5 of 24 swedish dissertations matching the above criteria.
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1. The role of chromatin in the induction and repair of DNA damage
Abstract : The role of chromatin in the induction and repair of DNA damage has a dual nature.The constituent proteins of chromatin protect the DNA against the induction of DNAdamage, while at the same time they reduce the accessibility of DNA to repair enzymes. READ MORE
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2. AtZDP, a Plant 3' DNA Phosphatase, Involved in DNA Repair
Abstract : DNA bases can be modified by endogenous agents (e.g. oxidized by products of respiration and photosynthesis or methylated by gene silencing processes) as well as by environmental agents (e.g. READ MORE
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3. Studies of DNA repair strategies in response to complex DNA damages
Abstract : The main aim of this thesis was to study the role of the indirect actions of γ-rays and α-particles on the complexity of primary DNA damages and the repair fidelity of major DNA repair pathways: non-homologous end joining (NHEJ), homologous recombination repair (HRR) and base excision repair (BER). The complexity of radiation-induced damages increases and the proximity between damages decreases with increasing LET due to formation of ionization clusters along the particle track. READ MORE
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4. Quantum Chemical Studies of Protein-Bound Chromophores, UV-Light Induced DNA Damages, and Lignin Formation
Abstract : Quantum chemical methods have been used to provide a better understanding of the photochemistry of astaxanthin and phytochromobilin; the photoenzymic repair of UV-light induced DNA damages; and the formation of lignin. The carotenoid astaxanthin (AXT) is responsible for the colouration of lobster shell. READ MORE
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5. Evolving the Methodology for Detection of Primary DNA Damage : Development, adaptation and assessment of the single cell gel electrophoresis (comet) assay
Abstract : Deoxyribonucleic acid (DNA) is one of the most important molecules in nature. It is the fundamental carrier of evolutionary information and constitutes the genetic blueprint of all living organisms. Being the sole source of information, it is vital for the cell to transmit the correct genetic information from generation to generation. READ MORE