Search for dissertations about: "dna markers"

Showing result 11 - 15 of 344 swedish dissertations containing the words dna markers.

  1. 11. Prognostic factors for squamous cell cervical cancer : tumor markers, hormones, smoking, and S-phase fraction

    Author : Annika Lindström; Dan Hellberg; Roger Henriksson; Ulf Stendahl; Sonia Andersson; Umeå universitet; []
    Keywords : Cervical cancer; squamous cell carcinoma; sex steroid hormones; smoking; S-phase fraction; tumor markers; LRIG1; prognosis.; MEDICINE; MEDICIN; Oncology; onkologi;

    Abstract : Cervical cancer is the second most common malignancy in women worldwide and one of the leading causes of cancer mortality globally. In patients with invasive cervical cancer prognostic factors are of value for the choice of treatment, monitoring of treatment and follow-up. READ MORE

  2. 12. DNA ploidy, proliferation markers and prognosis in malignant melanoma

    Author : Margareta Karlsson; Christer Lindholm; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Malignant melanoma is a serious disease when metastases occur. It is therefore important to investigate possible tools for prediction to the outcome of the disease. In the present investigation 265 patients with cutaneous malignant melanoma and uveal melanoma was investigated with flow cytometry. READ MORE

  3. 13. Markers predicting sensitivity to polyamine depletion in human breast cancer cell lines

    Author : Veronica Johansson; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; PCNA; PAO; human breast cancer cell lines; FEN1; DNA strand breaks; DNA ligase I; apoptosis; Bcl-2; polyamine analogues; pRb;

    Abstract : In spite of different treatment strategies today, breast cancer mortality is still high and new treatments are therefore needed. Potential new treatments can be found among the polyamine analogues. Polyamine analogues can be used in cancer treatment as cancer cells have a higher requirement for polyamines than the surrounding healthy tissue. READ MORE

  4. 14. Circulating markers of risk and etiology in colorectal cancer

    Author : Justin Harbs; Sophia Harlid; Bethany van Guelpen; Xijia Liu; Henrik Grönberg; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; CRC; sex hormones; colon cancer; DNA methylation; proteomics; risk; etiology; Cancer Epidemiology; cancerepidemiologi;

    Abstract : Background: Colorectal cancer is the third most commonly diagnosed cancer in men and women. Worldwide around 2 million individuals are diagnosed each year – a number expected to increase as colorectal cancer risk factors become more prevalent. READ MORE

  5. 15. DNA methylation as a prognostic marker i acute lymphoblastic leukemia

    Author : Magnus Borssén; Sofie Degerman; Kim Vettenranta; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA methylation; acute lymphoblastic leukemia; T-ALL; Relapse; Telomere length; patologi; Pathology; Pediatrics; pediatrik;

    Abstract : Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy. Most ALL cases originate from immature B-cells (BCP-ALL) and are characterized by reoccurring structural genetic aberrations. These aberrations hold information of the pathogenesis of ALL and are used for risk stratification in treatment. READ MORE