Search for dissertations about: "dna markers"

Showing result 6 - 10 of 344 swedish dissertations containing the words dna markers.

  2. 6. Prognostic markers and DNA methylation profiling in lymphoid malignancies

    Author : Sujata Bhoi; Richard Rosenquist Brandell; H Denis Alexander; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lymphoid malignancies; CLL; MCL; prognostic markers; micro-RNA; methylation; stereotyped subsets;

    Abstract : In recent years, great progress has been achieved towards identifying novel biomarkers in lymphoid malignancies, including chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL), at the genomic, transcriptomic and epigenomic level for accurate risk-stratification and prediction of treatment response. In paper I, we validated the prognostic relevance of a recently proposed RNA-based marker in CLL, UGT2B17, and analyzed its expression levels in 253 early-stage patients. READ MORE

  4. 7. Multiplex markers in a plant breeding perspective

    Author : Mats Hansen; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Plant biochemistry; plant breeding; SNP; RAPD; molecular markers; AFLP; Växtbiokemi;

    Abstract : Plant breeding is largely depending on the repeated selection for desirable traits. This process is both time and labour consuming, making the development of commercial plant varieties a slow and costly activity. READ MORE

  5. 8. Rectal Cancer - Tumor Biology and Prognostic Markers

    Author : Eva Fernebro; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prognostic markers; Cytology; oncology; cancerology; Cytologi; onkologi; cancer; immunohistochemistry IHC ; chromosomal instability CIN ; microsatellite instability MSI ; tissue microarray TMA ; tissue inhibitor of metalloproteinase 1 TIMP-1 ; Rectal cancer; soluble urokinase plasminogen activator receptor suPAR ;

    Abstract : Colorectal cancer is one of our most common malignancies and the second leading cause of cancer death worldwide. About 1/3 of the tumors are located in the rectum. READ MORE

  6. 9. Validation of Several Nucleoside Tracers as Proliferation Markers

    Author : Li Lu; Sven Reske; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biopharmacy; PET; cell proliferation; DNA synthesis; hydroxyurea; cimetidine; diuretic; Biofarmaci; Biopharmacy; Biofarmaci; galenisk farmaci; Pharmaceutics;

    Abstract : Positron emission tomography (PET) is a powerful method for in vivo characterization of tumor biochemistry and clinically has been used for diagnosing and grading of malignancy. A key element in oncology is proliferation potential, a feature that is assumed to be an important indicator of tumor growth. READ MORE

  7. 10. Application of Molecular Markers in Sugar Beet Breeding

    Author : Annika Hjerdin Panagopoulos; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Växtbiokemi; Plant biochemistry; breeding; marker application; molecular markers; sugar beet;

    Abstract : Around 1750 a German chemist discovered it to be possible to extract sugar crystals from beet juice. Since then, breeding and improved agricultural practices have increased the concentration of sucrose per root from around 4% to around 18%. READ MORE