Search for dissertations about: "dna sequence analysis"

Showing result 1 - 5 of 310 swedish dissertations containing the words dna sequence analysis.

  2. 1. Deciphering sequence data : A multivariate approach

    Author : Maria Sandberg Hiltunen; Michael Sjöström; Svante Wold; Lars Ståhle; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Principal properties; amino acids; nucleotides; tRNA; DNA; multivariate data analysis; sequence analysis; QSAR; quantitative sequence activity relationships;

    Abstract : In this thesis, attention has been focused on the quantitative description of nucleic acids, proteins and peptides. The strategy was to use multivariate chemometrical methods for improving the understanding of the complex structural codes of these kinds of biological molecules. READ MORE

  4. 2. Single DNA Molecule Analysis – New Tools for Medical Diagnosis

    Author : My Nyblom; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; optical DNA mapping; DNA damage; DNA; single-molecule analysis; fluorescence microscopy; antibiotic resistance; nanofluidics; genetics;

    Abstract : The DNA molecule, the blueprint of life, contains an enormous amount of information. The information is coded by the combination of four bases; adenine, cytosine, guanine, and thymine, that, together with the sugar-phosphate backbones, make up the DNA double helix. READ MORE

  5. 3. Selector Technology : For Multiplex DNA Analysis

    Author : Fredrik Dahl; Mats Nilsson; Ulf Landegren; Ivo Glynne Gut; Uppsala universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Genetic engineering; DNA technology; Genteknik; Genetic engineering including functional genomics; Genteknik inkl. funktionsgenomik;

    Abstract : A majority of methods for identifying sequences in the human genome involve target sequence amplification through PCR. This work presents novel methods for amplifying circularized DNA and presents solutions for some major limitations of PCR. READ MORE

  6. 4. Microfluidic bead-based methods for DNA analysis

    Author : Aman Russom; Ulf Gyllensten; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; single nucleotide polymorphism; DNA analysis; SNP; microfluidics; pyrosequencing; beads; lab on a chip; hybridization; DASH; microsystem; micro totat analysis system; allele-specific extension; DASH; microcontact printing; Genetik; Clinical genetics; Klinisk genetik;

    Abstract : With the completion of the human genome sequencing project, attention is currently shifting toward understanding how genetic variation, such as single nucleotide polymorphism (SNP), leads to disease. To identify, understand, and control biological mechanisms of living organisms, the enormous amounts of accumulated sequence information must be coupled to faster, cheaper, and more powerful technologies for DNA, RNA, and protein analysis. READ MORE

  7. 5. Sensitive Identification Tools in Forensic DNA Analysis

    Author : Hanna Edlund; Marie Allen; Niels Morling; Uppsala universitet; []
    Keywords : forensic genetics; STRs; Y-chromosome; Pyrosequencing; mitochondrial DNA; skeletal remains; DNA extraction; MEDICINE; MEDICIN; Medicinsk genetik; Medical Genetics;

    Abstract : DNA as forensic evidence is valuable in criminal investigations. Implementation of new, sensitive and fast technologies is an important part of forensic genetic research. This thesis aims to evaluate new sensitive methods to apply in forensic DNA analysis including analysis of old skeletal remains. READ MORE