Search for dissertations about: "doctoral thesis of diabetes"

Showing result 26 - 30 of 1938 swedish dissertations containing the words doctoral thesis of diabetes.

  2. 26. Expanding role of caveolae in control of adipocyte metabolism : proteomics of caveolae

    Author : Nabila Aboulaich; Peter Strålfors; Alexander Vener; Hans Jörnvall; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diabetes; Insulin signalling; Fatty acid metabolism; Proteomics; Mass spectrometry; Cell and molecular biology; Cell- och molekylärbiologi;

    Abstract : The primary function of adipose tissue is to store energy in the form of triacylglycerol, which is hydrolyzed to fatty acids to supply other tissues with energy. While insulin promotes the storage of triacylglycerol, catecholamines stimulate its hydrolysis. READ MORE

  4. 27. THE ROLE OF PHOSPHODIESTERASE 3B IN CAMP-MEDIATED REGULATION OF INSULIN SECRETION

    Author : Helena Jones; Signaltransduktionsforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cAMP; PDE3B; exocytosis; insulin; diabetes; Medicine human and vertebrates ; Medicin människa och djur ; diabetologi; sekretion; Endokrinologi; diabetology; Endocrinology; secreting systems;

    Abstract : Type 2 diabetes mellitus (T2DM) is characterized by various combinations of ?-cell failure and insulin resistance leading to hyperglycemia and glucose intolerance. In order to maintain glucose tolerance in the insulin resistance state, increased insulin secretion is a requirement and it is because of inadequate islet adaptation that glucose intolerance develops in T2DM. READ MORE

  5. 28. Mechanisms of insulin exocytosis and release

    Author : Sebastian Barg; Islet cell physiology; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ClC-3; electrophyiology; confocal microscopy; calcium channel; readily releasable pool; exocytosis; insulin; diabetes; green fluorescent protein; Physiology; Fysiologi;

    Abstract : Endocrine cells as well as neurons release their hormones and transmitters by regulated exocytosis. In the pancreatic B-cell, stimuli like glucose initiate biochemical and electrical processes that culminate in influx of Ca2+, which then triggers exocytosis of insulin-containing granules. READ MORE

  6. 29. On the effects of obesity treatment

    Author : Gudrun Höskuldsdóttir; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; Diabetes; Bariatric surgery;

    Abstract : Aim: In this thesis the effects of bariatric surgery in individuals with type 1 diabetes (T1D) will be assessed as well as the effects of surgery on risk for heart failure (HF) and atrial fibrillation (AF) in individuals with type 2 diabetes (T2D). Intensive medical treatment of obesity will be compared with the most common surgical methods and factors predicting obesity and treatment outcomes evaluated. READ MORE

  7. 30. Bariatric surgery as treatment of type 2 diabetes – clinical and mechanistic aspects

    Author : Petros Katsogiannos; Jan Eriksson; Magnus Sundbom; Per-Ola Carlsson; Daniel Andersson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Roux-en-y gastric bypass; Type 2 diabetes; incretins; cytokines; adipokines; adipose tissue; heart rate variability; quality of life.; Medicinsk vetenskap; Medical Science;

    Abstract : Bariatric surgery can rapidly improve glycemic control and cardiovascular risk factors in patients with T2D and obesity. These improvements appear to be partly independent of weight loss, however, the underlying mechanisms remain incompletely understood. READ MORE