Search for dissertations about: "doctoral thesis of diabetic nephropathy"

Showing result 1 - 5 of 47 swedish dissertations containing the words doctoral thesis of diabetic nephropathy.

  1. 1. Pathomechanism of diabetic nephropathy

    University dissertation from Stockholm : Karolinska Institutet, Department of Women's and Children's Health

    Author : Anna Körner; Karolinska Institutet.; Karolinska Institutet.; [1999]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetic nephropathy; hyperflltration; Na ; K - ATPase; Dahl rats; salt sensitive hypertension; glomerulosclerosis; polyol pathway activation; oxidative stress;

    Abstract : Diabetic nephropathy is today the most common cause of end stage renal failure. The risk for developing overt diabetic nephropathy is considerably reduced by antihypertensive treatment, and adequate control of blood glucose. However, there is a need for additional and even more efficient tools to prevent this complication of diabetes. READ MORE

  2. 2. Factors influencing the risk of diabetic nephropathy analyses of genes, smoking and diet

    University dissertation from Umeå : Klinisk vetenskap

    Author : Anna Möllsten; Umeå universitet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 1 diabetes; diabetic nephropathy; oxidative stress; smoking; diet; blood pressure; renin-angiotensin system; nitric oxide synthase; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Kidney diseases; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Njursjukdomar;

    Abstract : Diabetic long-term complications, despite intensive treatment, cause serious handicaps at relatively young age in diabetic patients. Diabetic nephropathy (DN) develops in up to 30% of patients with type 1 diabetes (T1D). READ MORE

  3. 3. The role of hypoxia for the development of diabetic nephropathy Temporal relationship and involvement of endothelin receptor signaling

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Stephanie Franzén; Linköpings universitet.; Linköpings universitet.; Linköpings universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nephropathy; diabetes; hypoxia; EPR;

    Abstract : Diabetic nephropathy is one of the most common causes of end stage renal disease and develops in approximately one third of all diabetes patients. Disease progression is characterized by deteriorating glomerular filtration rate and escalating urinary albumin/protein excretion; both are used as clinical markers for disease progression. READ MORE

  4. 4. Aspects of Regulation of GFR and Tubular Function in the Diabetic Kidney Roles of Adenosine, Nitric Oxide and Oxidative Stress

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Patrik Persson; Uppsala universitet.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetes; diabetic nephropathy; glomerular filtration rate; renal blood flow; insulin; renal hemodynamics; micropuncture; oxygen; NADPH-oxidase; apocynin; streptozotocin; l-arginine; CGS21680; rats; mice; Physiology; Fysiologi; Medical Science; Medicinsk vetenskap;

    Abstract : Diabetic nephropathy is the main cause for initiation of renal replacement therapy and early symptoms in patients include increased glomerular filtration rate (GFR), decreased oxygen tension and albuminuria, followed by a progressive decline in GFR and loss of kidney function. Experimental models of diabetes display increased GFR, decreased tissue oxygenation and nitric oxide bioavailability. READ MORE

  5. 5. The Role of Mitochondrial Uncoupling in the Development of Diabetic Nephropathy

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Malou Friederich Persson; Uppsala universitet.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kidney; mitochondria; Uncoupling Protein-2; Adenosine Nucleotide Transporter; uncoupling; diabetes; diabetic nephropathy; db db; dinitrophenol; Coenzyme Q10; oxygen; rats; mice; Physiology; Fysiologi; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : Diabetes is closely associated with increased oxidative stress, especially originating from the mitochondria. A mechanism to reduce increased mitochondria superoxide production is to reduce the mitochondria membrane potential by releasing protons across the mitochondria membrane. READ MORE