Search for dissertations about: "doctoral thesis of diabetic nephropathy"

Showing result 16 - 20 of 57 swedish dissertations containing the words doctoral thesis of diabetic nephropathy.

2. 16. Identification of the susceptibility genes in type 1 diabetes and diabetic nephropathy

   Author : Jun Ma; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Type 1 Diabetes; Diabetic Nephropathy; Genetic Association; Single Nucleotide Polymorphism;

   Abstract : Genetic susceptibility plays an important role in the pathogenesis of type 1 diabetes (T1D) and diabetic nephropathy (DN). The present study aims to investigate the association between single nucleotide polymorphisms (SNPs) in candidate genes and DN. READ MORE

4. 17. Genetic and functional analyses of diabetic nephropathy with focus on chromosome 3q

   Author : Dongying Zhang; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Diabetic nephropathy; chromosome 3; single nucleotide polymorphism; genetic association; gene expression;

   Abstract : Diabetic nephropathy (DN) is a complex disease affected by both genetic and environmental factors. Genetic and functional analyses of the susceptibility and/or resistance genes in DN may provide useful information for better understanding the pathogenesis and further developing novel therapeutic approaches in this disease. READ MORE

5. 18. Diabetes-induced Alterations in Renal Microcirculation and Metabolism

   Author : Fredrik Palm; Per Liss; Peter Hansell; Per-Ola Carlsson; Gerald DiBona; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; diabetes mellitus; kidney; nephropathy; oxygen tension; haemodynamic; nitric oxide; oxygen consumption; radical oxygen species; polyol pathway; Fysiologi; Physiology; Fysiologi;

   Abstract : Diabetes-induced renal complications, i.e. diabetes nephropathy, are a major cause of morbidity and mortality. The exact mechanism mediating the negative influence of hyperglycaemia on renal function is unclear, although several hypotheses have been postulated. READ MORE

6. 19. Regulatory T cells in type 1 diabetes: the role of IL-35 in counteracting the disease

   Author : Kailash Singh; Thomas Mandrup-Poulsen; Uppsala universitet; []
   Keywords : IL-35; regulatory T cells; type 1 diabetes; LADA; kidney and diabetic nephropathy; Medicinsk vetenskap; Medical Science; Immunologi; Immunology; Endocrinology and Diabetology; Endokrinologi och Diabetologi;

   Abstract : Type 1 diabetes (T1D) is etiologically considered as an autoimmune disease, where insulin-producing β-cells are damaged by autoimmune attacks. Regulatory T (Treg) cells are immune homeostasis cells. In the present thesis I aimed to investigate the role of Treg cells and other immune cells in the early development of T1D. READ MORE

7. 20. Diabetic glomerulopathy-natural history, intervention and prediction of complications

   Author : Nina Perrin; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Type 1 diabetes; adolescents; normoalbuminuria; normotension; glomerulopathy; kidney biopsy; ambulatory blood pressure measurement; kidney function tests; risk factors; microalbuminuria; hypertension;

   Abstract : Diabetes mellitus is one of the most common chronic diseases in childhood. Diabetic nephropathy (DN) is one of the threatening complications of diabetes that occurs in 30-40% of patients after 20 years duration of disease. READ MORE