Search for dissertations about: "dorsal"

Showing result 6 - 10 of 350 swedish dissertations containing the word dorsal.

2. 6. Stem Cell Transplantation in Dorsal Root Injury

   Author : Carl Trolle; Elena Kozlova; Niklas Marklund; Karin Nordström; Michael Andäng; Mårten Risling; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sensory Neuron; Regeneration; Spinal Root; Stem Cell; Neuroscience; Neurovetenskap;

   Abstract : After traumatic injuries to the brachial plexus there is a risk that one or more of the spinal roots are torn from the spinal cord, known as avulsion injury. This often leads to paralysis and chronic pain, notoriously difficult to treat with current pharmacotherapy. READ MORE

4. 7. Galanin in the rat dorsal spinal cord : an inhibitor peptide in sensory processing

   Author : Katarina Bedecs; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES;

   Abstract : .... READ MORE

5. 8. Transcriptional and epigenetic control of gene expression in embryo development

   Author : Ann Boija; Mattias Mannervik; Jerry L. Workman; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Epigenetics; Cell specification; Drosophila embryo; Dorsal morphogen; CBP p300; Gene regulation; Chromatin; Promoter proximal Pol II pausing; utvecklingsbiologi; Developmental Biology;

   Abstract : During cell specification, temporal and spatially restricted gene expression programs are set up, forming different cell types and ultimately a multicellular organism. In this thesis, we have studied the molecular mechanisms by which sequence specific transcription factors and coactivators regulate RNA polymerase II (Pol II) transcription to establish specific gene expression programs and what epigenetic patterns that follows. READ MORE

6. 9. Neurobiological Consequences of Social Conditions and Alcohol Exposure in Adolescent rats

   Author : Linnea Granholm; Ingrid Nylander; Anne-Lie Svensson; Erika Roman; Maria Ellgren; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adolescence; alcohol; amphetamine; dopamine; dorsal striatum; dynorphin; endogenous opi- oids; enkephalin; high-speed chronoamperometry; housing conditions; rats; nociceptin orphanin FQ; radi- oimmunoassay; self-administration; Farmaceutisk vetenskap; Pharmaceutical Science;

   Abstract : Adolescence represents a time of extensive reorganisation and maturation of brain circuits involved in emotions, motivation and cognition and it is a period particular sensitive for external stimuli. External stimuli can be both socio-environmental factors and exposure to exogenous compounds such as drugs of abuse (e.g. alcohol). READ MORE

7. 10. Targeting and driving somatosensory neurons

   Author : Fabio Freitag; Malin C. Lagerström; Andrew Todd; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pain; Itch; GRPR interneurons; dorsal horn; trigeminal nucleus caudalis; Barrel field;

   Abstract : Pain and itch are two distinct sensations, but the fundamental question of how our nervous system distinguishes the processing and encoding of their related information is still far to be clearly delineated. At the spinal cord level, evidences have pointed out specific groups of neurons expressing the gastrin releasing peptide (Grp) and its receptor (Grpr) as responsible for carrying specifically itch-related information. READ MORE