Search for dissertations about: "dose adaptation"
Showing result 1 - 5 of 24 swedish dissertations containing the words dose adaptation.
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1. Dose Adaptation Based on Pharmacometric Models
Abstract : Many drugs exhibit major variability in both pharmacokinetic (PK) and pharmacodynamic (PD) parameters that prevents the use of the same dose for all patients. Variability can occur both between patients (IIV) as well as within patients over the course of time (IOV). READ MORE
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2. Pharmacometric Approaches to Improve Dose Individualization Methods in Hemophilia A
Abstract : Hemophilia A is a bleeding disorder caused by the lack of functional coagulation factor VIII (FVIII). The overall aim of this thesis was to improve dose individualization of FVIII replacement therapy in hemophilia A using pharmacometric approaches. READ MORE
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3. Cone Beam Computed Tomography - radiation dose and image quality assessments
Abstract : Diagnostic radiology has undergone profound changes in the last 30 years. New technologies are available to the dental field, cone beam computed tomography (CBCT) as one of the most important. READ MORE
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4. Effects of some ward routines on behavioural and physiological adaptation to breast-feeding
Abstract : The overall aim of this thesis was to study how early breast-feeding would be influenced by pethidine given during labour and by an emergency Caesarean section. Eighteen mother-infant pairs which were exposed and 26 which were not exposed to pethidine during labour were observed the first two hours after birth. READ MORE
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5. Mechanisms of adaptation in a mechanoreceptor : a study of mechanical and ionic factors in the crayfish stretch receptors
Abstract : The stretch receptor organ of the crayfish, an analog to the human muscle spindle, is a unique preparation for the study of mechanotransduction. The organ consists of a rapidly and a slowly adapting receptor each composed of a receptor muscle fibre into which inserts the dendrites of a multipolar sensory neuron. READ MORE