Search for dissertations about: "dose and side effect data"

Showing result 1 - 5 of 49 swedish dissertations containing the words dose and side effect data.

2. 1. Radiation Oncology Data and Modelling Side Effects after Radiation Therapy

   Author : Caroline Olsson; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; dose and side effect data; dose-volume response; fractionation effect; LQ model; sequential two-phase radiotherapy; head and neck cancer; parotid gland; xerostomia; pelvic radiotherapy; gynecological cancer; pubic bone; pain; data integration; xerostomia;

   Abstract : Although modern radiation therapy techniques have the ability to conform the dose distribution of ionizing radiation tightly around the volume to be treated, unwanted irradiation to surrounding organs remains a problem. The probability of a side effect arising in the normal tissue of a patient after radiation therapy can be modelled by sigmoid mathematical functions known as normal tissue complication probability (NTCP) models. READ MORE

4. 2. Optimizing levodopa dosing routines for Parkinson’s disease

   Author : Ilias Thomas; Jerker Westin; Moudud Alam; Alexander Medvedev; Högskolan Dalarna; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Parkinson’s disease; levodopa; symptom assessment; symptom management; dosing algorithms; wearable sensors; microtablets; continuous infusion; FLOAT - Flexible Levodopa Optimizing Assistive Technology; FLOAT - Flexibel levodopa-optimerings och individanpassningsteknik;

   Abstract : This thesis in the field of microdata analysis aims to introduce dose optimizing algorithms for the pharmacological management of Parkinson’s disease (PD). PD is a neurodegenerative disease that mostly affects the motor functions of the patients and it is characterized as a movement disorder. READ MORE

5. 3. Predicting Normal Tissue Complications after External Beam Radiation Therapy

   Author : Caroline Olsson; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NTCP; fractionation effects; radiobiological modelling; pubic bone pain;

   Abstract : Although modern external beam radiation (EBRT) therapy has the ability to conform the dose tightly around the volume to be treated, unwanted irradiation to surrounding normal tissue is still a problem. The probability of a side effect arising in normal tissue after EBRT is commonly modelled by an s-shaped dose-volume response curve where dose or volume are plotted against response (i. READ MORE

6. 4. On the efficacy and prescription of serotonin reuptake inhibitors

   Author : Alexander Lisinski; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antidepressants; antidepressive agents; major depressive disorder; selective serotonin reuptake inhibitor; serotonin and noradrenaline reuptake inhibitor; tricyclic antidepressant;

   Abstract : This thesis addresses several controversial issues regarding commonly used antidepressants, including selective serotonin reuptake inhibitors (SSRIs), serotonin and noradrenaline reuptake inhibitors (SNRIs), and tricyclic antidepressants (TCAs). To this end, patient-level data from 28 placebo-controlled trials on SSRIs and 13 corresponding trials on the SNRI duloxetine, were requested and obtained. READ MORE

7. 5. Epidemiological studies of risk factors for injuries in an adult population

   Author : Birgit Modén; Socialmedicin och hälsopolitik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epidemiologi; injury; accident; sociodemographic factors;

   Abstract : Injuries are often associated with long-term suffering and lowered functioning, and personal injuries impose a huge burden on medical care and health services in addition to the costs associated with impaired functional ability. Each year in Sweden, falling accidents are experienced by a third of those aged 60 or over and half of those aged 80 or over, while injuries from traffic accidents still account for many of the serious accidents in youths and younger adults. READ MORE