Search for dissertations about: "dried blood spots"

Showing result 11 - 15 of 21 swedish dissertations containing the words dried blood spots.

  2. 11. Posterior ocular malformations in children : teratological aspects

    Author : Kristina Teär Fahnehjelm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Teratology; ocular malformations; visual impairment; anti-epileptic drugs; congenital infection; optic nerve hypoplasia; coloboma; magnetic resonance imaging; neonatal cholestasis; dried blood spots;

    Abstract : Posterior ocular malformations are common causes of visual impairment in Swedish children. The most frequent diagnoses within this group are optic nerve hypoplasia and optic nerve/chorioretinal coloboma. Genetic factors, teratogens like medical/addictive drugs or congenital infections and unknown factors may cause these malformations. READ MORE

  4. 12. Prognostic molecular markers of childhood leukemia

    Author : Fredrika Gauffin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Acute lymphoblastic leukemia; dic 9; 20 ; dried blood spots; Guthrie card; RNA; PTEN; SHP1; VEGF; VEGFR-1; VEGFR-2; immuhistochemistry; tissue micro array;

    Abstract : During the last decades there has been a dramatic increase in survival rates for childhood leukemia, resulting today in an overall survival close to 90 % for children with acute lymphoblastic leukemia (ALL). This accomplishment is largely due to treatment protocols based on careful risk group assessment guiding the type and intensity of the anti-leukemic treatment. READ MORE

  5. 13. Population genetic, association and zygosity testing on preamplified DNA

    Author : Ulf Hannelius; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : New advances in genetic epidemiological research have lead to the establishment of collaborative biobanks that can be used in large-scale population genetic and association studies. A less explored approach is to use the existing biological repositories, like the Swedish newborn screening registry (SNSR) for similar purposes. READ MORE

  6. 14. From Lab to Chip – and back : Polymer microfluidic systems for sample handling in point-of-care diagnostics

    Author : Jonas Hansson; Wouter van der Wijngaart; Hywel Morgan; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Electrical Engineering; Elektro- och systemteknik;

    Abstract : This thesis contributes to the development of Lab-on-a-Chip systems that enables reliable, rapid medical diagnostics at the point-of-care. These contributions are focused on microfluidic Lab-on-a-Chip systems for sepsis diagnosis, autonomous sample-to-answer tests, and dried blood spot sampling. READ MORE

  7. 15. Development of screening for primary immunodeficiency

    Author : Magdalena Janzi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Primary immunodeficiencies are inherited disorders of the immune system, with an estimated prevalence of 1:500 in the USA. Yet, a majority of the patients are still undiagnosed. Most patients with a diagnosis come in contact with the healthcare due to complications caused by the immunological defects. READ MORE