Search for dissertations about: "dried blood spots"

Showing result 6 - 10 of 21 swedish dissertations containing the words dried blood spots.

  1. 6. Drug Analysis : Bioanalytical Method Development and Validation

    Author : Mikaela Malm; Yngve Bergqvist; Anders Colmsjö; Uppsala universitet; []
    Keywords : Analytical chemistry; African trypanosomiasis; calibration model; chiral chromatography; dried blood spots; eflornithine; evaporative light-scattering detection; HIV AIDS; lamivudine; liquid chromatography; malaria; nevirapine; piperaquine; pneumonia; solid-phase extraction; sulfadoxine; sulfamethoxazole; validation; zidovudine; Analytisk kemi;

    Abstract : This thesis describes bioanalytical methods for drug determination in biological matrixes, with drugs in focus used against diseases largely affecting low-income countries. Solid-phase extraction is used for sample cleanup, and processed samples are analyzed by liquid chromatography. READ MORE

  2. 7. Usefulness of archival biobank samples for genetic epidemiologic studies

    Author : Malin Sjöholm; Malmö Klinisk mikrobiologi; []
    Keywords : formailn-fixed paraffin-embedded tissue; biobank; serum; dried blood spots; plasma; archival samples;

    Abstract : Sweden has a long history of maintaining population-based registries and biobanks. This has resulted in large sample collections with long follow-up and large numbers of prospectively occurring disease endpoints providing an extensive resource for genetic research. READ MORE

  3. 8. Fluorescent quantum dots and graphene-based sensors for forensic applications

    Author : Johnny Jussi; Ying Fu; Simon Dunne; Qin Wang; Ingemar Petermann; Xin Wang; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Graphene; Quantum Dots; Blood; Forensics; Drugs; Biologisk fysik; Biological Physics;

    Abstract : A key emerging concept within the forensic sciences today areportable measurementdevices, where a much more efficient usage of the resources involved with crime-solving is possible if confirmatory measurements can be realised directly at a crimescene with such devices. Today, the majority of the presently used methods duringcriminal investigation at a crime scene involves measurements of a presumptivenature, which is a vital tool as it enables the screening of samples. READ MORE

  4. 9. Development of field-adapted analytical methods for the determination of new antimalarial drugs in biological fluids

    Author : Niklas Lindegårdh; Högskolan Dalarna; []
    Keywords : LC; liquid chromatography; biological samples; SPE; solid phase extraction; validation; antimalarial drugs; amodiaquine; piperaquine; atovaquone; dried blood spots;

    Abstract : .... READ MORE

  5. 10. Possibilities of dried blood spots as a matrix in therapeutic drug monitoring of antiepileptic drugs in children

    Author : Camilla Linder; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : For children with epilepsy, therapeutic drug monitoring (TDM) of antiepileptic drugs (AEDs) is essential for treatment. TDM monitoring requires two visits to a health care unit, first for collection of the blood sample before the morning dose and a few days later the family will travel once again to see the pediatrician. READ MORE