Search for dissertations about: "drosophila cancer"

Showing result 1 - 5 of 33 swedish dissertations containing the words drosophila cancer.

  2. 1. Wnt-5a Signalling in Human Mammary Cells: Implications for the Development of Breast Cancer

    Author : Marzieh Jönsson; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; Cytology; signalling; breast cancer; Wnt-5a; mammary epithelial cells; cancer; onkologi; Cytologi; cancerology;

    Abstract : The Wnt-5a gene encodes a secreted protein that regulates several normal processes in embryonic and adult tissues by as yet unknown mechanisms. Expression of Wnt-5a protein does not cause cell transformation, but it instead counteracts the effects induced by transforming Wnts. READ MORE

  4. 2. Stress and immune signaling in a Drosophila tumor model

    Author : Dilan Khalili; Ulrich Theopold; Mirka Uhlirova; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drosophila; cancer; innate immunity; fibrosis; antimicrobial peptides; chitinase-like proteins; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Cancer cells contain multiple biological alterations that allow them to escape from host surveillance mechanisms. One of the mechanisms that play an essential role in host protection against tumor growth is immunity. READ MORE

  5. 3. Genomic adaptation and gene-dosage regulation of Drosophila melanogaster cells, and long-read software developments

    Author : Jacob Lewerentz; Per Stenberg; Jan Larsson; Bergman Casey; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Drosophila; cell line; long read; Nanopore; Pacbio; Illumina; cancer; genome evolution; dosage compensation; structural variant; software; bioinformatics;

    Abstract : Cells are the vehicles that allows genetic code to proliferate in the world, taking on various forms – as illustrated by the tree of life. The cell features are determined by the manufacturing of proteins, a process that has its blueprints encoded as genes in the genome. READ MORE

  6. 4. bHLH transcription factors in differentiating neuroblastoma cells

    Author : Anna Grynfeld; Avdelningen för molekylärmedicin och genterapi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bHLH; Neuroblastoma; HES-1; HASH-1; N-Myc; differentiation; Mad; Medicine human and vertebrates ; Medicin människa och djur ;

    Abstract : Neuroblastoma is a tumor of the sympathetic nervous system, and arises during early childhood. The tumor is highly heterogeneous and evidence, such as expression of genes normally only expressed during embryonic and fetal stages, suggests that the tumor is of embryonic origin and that the tumor arises as a consequence of perturbed differentiation during the development of the sympathetic nervous system. READ MORE

  7. 5. Molecular characterization of the Drosophila responses towards nematodes

    Author : Md. Badrul Arefin; Ulrich Theopold; Ioannis Eleftherianos; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Drosophila; nematodes; infection; danger situations; immune response; coagulation; apoptosis; nitric oxide; leukemia; Molecular Biology; molekylärbiologi;

    Abstract : A sophisticated evolutionary conserved innate immune system has evolved in insects to fight pathogens and to restrict damage in harmful (danger) situations including cancer. A significant amount of knowledge about different infection models in Drosophila has been generated in past decades, which revealed functional resemblances and implications for vertebrate systems. READ MORE