Search for dissertations about: "drug ,surfactant interaction"

Showing result 1 - 5 of 9 swedish dissertations containing the words drug ,surfactant interaction.

2. 1. Topical formulations, design and drug delivery : "A dive into water"

   Author : Abdullah Ali; Marie Lodén; Anan Yagmur; Anders Hall; Malmö universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; water; topical formulations; Pickering emulsion; skin cream; drug delivery; tactile friction; sensory panel; nasal; buccal; mucosa; skin; triglycerides; ethanol; drug transport; cosmetic appeal;

   Abstract : Water is a vital component regulating the properties of topical formulations and their interaction with biological barriers, such as skin and mucosa. Changing the watercontent within the frame of the pharmaceutical triangle will have a huge impact on which type of formulation, such as a cream, ointment, gel, or lotion, is formed, as well as the physical properties of the formulation. READ MORE

4. 2. Characterisation of Aqueous Solutions, Liquid Crystals and Solid State of Non-ionic Polymers in Association with Amphiphiles and Drugs

   Author : Annika Ridell; Martin Malmsten; Sven Engström; David Attwood; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; polymer; surfactant; phase diagram; x-ray diffraction; fluorescence spectroscopy; calorimetry; PEG; cellulose ether; viscometry; cubic phase; liquid crystals; drugs; solid dispersion; Fysikalisk kemi; Physical chemistry; Fysikalisk kemi; Fysikalisk och oorganisk farmaceutisk kemi; Physical and Inorganic Pharmaceutical Chemistry;

   Abstract : Cellulose ethers and polyethylene glycols are used in drug formulations as water swelling or water soluble matrices. Polar lipids, for example monoglycerides, and surfactants can be used to solubilise hydrophobic or amphiphilic drugs and to formulate potential drug delivery vehicles such as emulsions, liposomes and cubic phases. READ MORE

5. 3. Catanionic Aggregates in Gels : Prolonged Drug Release and Potential Implications for Topical Use

   Author : Noel Dew; Erik Björk; Stefan Ulvenlund; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; Galenisk farmaci; Galenisk farmaci; Pharmaceutics;

   Abstract : Gels are popular dosage forms.  This topical dosage form may be advantageous compared to oral or parenteral dosage forms. Favorable rheological or bioadhesive properties of gels might provide extended contact times at the site of administration compared to aqueous solutions. READ MORE

6. 4. A structural investigation into the complexity of mesoporous silica crystals : From a view of curvature and micellar interaction to quasicrystallinity

   Author : Changhong Xiao; Terasaki Osamu; Lidin Sven; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; electron microscopy; mesoporous silica; quasicrystal; minimal surface; Structural Chemistry; strukturkemi;

   Abstract : Mesoporous silica crystals have a large variety of structures mainly due to the versatility of their structure template. The configuration and the chemical state of the templating micellar surfactants, together with the kinetic process of silica will determine the final outcome of the synthesis. READ MORE

7. 5. Molecular dynamics and aggregation behaviour in aqueous polymer-drug model systems

   Author : Hans Evertsson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi; Physical and Inorganic Pharmaceutical Chemistry; fysikalisk och oorganisk farmaceutisk kemi;

   Abstract : Pharmaceutical formulations often contain polymers used as binders, swelling agents, etc., to give the formulation mechanical stability or specific drug release features. Many drug substances, as well as polymers, are amphiphilic which will give an associative polymer-drug interaction, affecting the dissolution rate and drug release. READ MORE