Search for dissertations about: "drug control"

Showing result 1 - 5 of 614 swedish dissertations containing the words drug control.

  2. 1. Management control and strategy : a case study of pharmaceutical drug development

    Author : Fredrika Berglund; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Management control systems; Tight control; Loose control; Interactive control; Diagnostic control; Budget; Portfolio management; Project management; Goals and Objectives systems; Business strategy; Research Development; Pharmaceutical; Computer science; Datavetenskap; Economic Information Systems; Ekonomiska informationssystem;

    Abstract : How are formal management controls designed and used in research & development (R&D)? The purpose of this study is to explain how such systems are designed and used in formulating and implementing strategies in a pharmaceutical product development organisation. The study uses a contingency approach to investigate how the control system is adjusted to the business strategy of the firm. READ MORE

  4. 2. Nonlinear Modeling and Feedback Control of Drug Delivery in Anesthesia

    Author : Margarida M. Silva; Alexander Medvedev; Teresa Mendonça; Torbjörn Wigren; Robain De Keyser; Uppsala universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; anesthesia; drug delivery; feedback control; nonlinear modeling; pharmacokinetics pharmacodynamics; PID control; system identification; Wiener model; Elektroteknik med inriktning mot reglerteknik; Electrical Engineering with specialization in Automatic Control;

    Abstract : General anesthesia is a drug-induced reversible state where neuromuscular blockade (NMB), hypnosis, and analgesia (jointly denoted by depth of anesthesia - DoA) are guaranteed. This thesis concerns mathematical modeling and feedback control of the effect of the muscle relaxants atracurium and rocuronium, the hypnotic propofol, and the analgesic remifentanil. READ MORE

  5. 3. Studies of Retroviral Reverse Transcriptase and Flaviviral Protease Enzymes as Antiviral Drug Targets : Applications in Antiviral Drug Discovery & Therapy

    Author : Muhammad Junaid; Jarl ES Wikberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Virus; enzymes; HIV AIDS; retroviral reverse transcriptase; flaviviral protease; NRTIs; proteochemometrics; drug resistance; DEN; JEV; NS2B H -NS3pro; antiviral; drug targets; drug discovery; drug therapy.; Farmakologi; Pharmacology;

    Abstract : Viruses are a major threat to humans due to their unique adaptability, evolvability and  capability to control their hosts as parasites and genetic elements. HIV/AIDS is the third largest cause of death by infectious diseases in the world, and drug resistance due to the viral mutations is still the leading cause of treatment failure. READ MORE

  6. 4. Drug Metabolites Formed by Cunninghamella Fungi : Mass Spectrometric Characterization and Production for use in Doping Control

    Author : Axel Rydevik; Mikael Hedeland; Ulf Bondesson; David Cowan; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cunninghamella blakesleeana; Cunninghamella elegans; Doping Control; Drug Metabolites; Glucuronide Production; Mass Spectrometry; Reactive Metabolites; Reference Material; Structural Characterization; Analytical Pharmaceutical Chemistry; Analytisk farmaceutisk kemi;

    Abstract : This thesis describes the in vitro production of drug metabolites using fungi of the Cunninghamella species. The metabolites were characterized with mainly liquid chromatography-mass spectrometry using ion-trap and quadrupole-time-of-flight instruments. A fungal in vitro model has several advantages e.g. READ MORE

  7. 5. Asthma in Primary Care : Severity, Treatment and Level of Control

    Author : Björn Ställberg; Gunnar Johansson; Kurt Svärdsudd; Bo Lundbäck; Eva Rönmark; Olle Zetterström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adherence; adolescent; adult; asthma; asthma classification; asthma control; asthma severity; compliance; drug therapy; hyperresponsiveness; primary health care; smoking; asthma treatment.; Family medicine; Allmänmedicin;

    Abstract : Aims. The overall aim was to examine the severity, treatment and level of control in patients with asthma in primary care in Sweden. READ MORE