Search for dissertations about: "drug eluting stent"

Showing result 1 - 5 of 6 swedish dissertations containing the words drug eluting stent.

2. 1. Genetic studies on cardiovascular disease - identification of novel drug targets

   Author : Stefan Amisten; Kardiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Medicin människa och djur ; Medicine human and vertebrates ; platelet; single nucleotide polymorphism; myocardial infarction; stent; G-protein coupled receptor; P2Y; cytogenetics; Genetik; cytogenetik; Cardiovascular system; Kardiovaskulära systemet;

   Abstract : The aim of this thesis was to identify novel potential drug targets of cardiovascular disease with a focus on G-protein coupled receptors. We identified a common genetic variant of the ATP receptor P2Y11, where an alanine is substituted with a threonine at position 87 of the P2Y11 receptor that increases the risk of developing acute myocardial infarction. READ MORE

4. 2. Invasive treatment of coronary artery disease : Aspects on antithrombotic and percutaneous treatment options

   Author : Per Grimfjärd; Stefan James; Christoph Varenhorst; P Hedberg; Lene Holmvang; Uppsala universitet; []
   Keywords : PCI; STEMI; stent thrombosis; bivalirudin; heparin; bioresorbable scaffold; cangrelor; drug eluting stent; DES; Cardiology; Kardiologi;

   Abstract : The outcome after percutaneous coronary intervention (PCI) has improved considerably thanks to more effective antithrombotic treatment strategies and improved coronary stents. Stent thrombosis (ST) is a rare complication to PCI associated with considerable mortality and morbidity. READ MORE

5. 3. Coronary artery disease and prognosis in relation to cardiovascular risk factors, interventional techniques and systemic atherosclerosis

   Author : Fredrik Calais; Ole Fröbert; Jerzy Leppert; Bo Lagerqvist; Stefan K James; Douwe E. Atsma; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atherosclerosis; Myocardial infarction; Coronary artery disease; Extra-cardiac artery disease; Coronary stent; Thrombus aspiration; physical inactivity; Prognosis;

   Abstract : Aim: To evaluate the prognosis associated with location and severity of coronary and systemic atherosclerosis in patients with coronary artery disease (CAD) in relation to risk factors and interventional techniques.Methods: The thesis comprised six longitudinal studies based on three patient cohorts: The Swedish Coronary Angiography and Angioplasty Registry, the Västmanland Myocardial Infarction Survey, and the Thrombus Aspiration in ST-Elevation myocardial infarction in Scandinavia study, to evaluate clinical outcome relative to coronary lesion location and severity, extracoronary artery disease (ECAD), intervention techniques, and leisuretime physical inactivity (LTPI). READ MORE

6. 4. On cardiovascular complications in people with type 2 diabetes : Aspects of incretin-based therapy and glycemic control

   Author : Irene Santos Pardo; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Background: Hyperglycemia, insulin resistance, and the presence of advanced glycation end products are key features of type 2 diabetes (T2DM) and the leading mechanisms behind the increased cardiovascular risk observed in people with this condition. Percutaneous coronary revascularization has been associated with higher risk of stent failure in people with diabetes mellitus (DM), having greater risk of both in-stent restenosis (ISR) and stent thrombosis (ST). READ MORE

7. 5. Influence of chronic kidney disease on presentation, treatment and outcome in patients with coronary artery disease

   Author : Robert Edfors; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Background. About one third of patients with myocardial infarction (MI) have renal dysfunction (RD). Concomitant coronary artery disease (CAD) and RD is accompanied by a markedly higher risk of death and subsequent cardiovascular (CV) events. READ MORE