Search for dissertations about: "drug susceptibility testing"

Showing result 1 - 5 of 25 swedish dissertations containing the words drug susceptibility testing.

2. 1. Tuberculosis : diagnosis and drug susceptibility testing where resources are scarce

   Author : Kristian Ängeby; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Tuberculosis; diagnosis; microscopy; drug susceptibility testing; low-income countries;

   Abstract : Background: Tuberculosis remains a major global public health problem. Not surprisingly, most cases of this disease occur in poor countries and an increasing number of patients harbor drug - resistant bacteria. The cornerstone of bacteriological diagnosis of tuberculosis is direct sputum smear microscopy. READ MORE

4. 2. Species specific susceptibility testing for ß-lactam antibiotics. With special reference to staphylococci

   Author : Ann Cathrine Petersson; Avdelningen för medicinsk mikrobiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bakteriologi; mycology; Mikrobiologi; virology; bacteriology; beta-lactamase; staphylococcus; methicillin resistance; Microbiology; mecA susceptibility testing; virologi; mykologi;

   Abstract : The main objective of this thesis was to identify methods for the detection of ß-lactam resistance in staphylococci, bacteria often causing nosocomial infections. Detection of ß-lactam resistance in these species is difficult due to strong regulation of genes encoding for the two main resistance mechanisms, ß-lactamase production and the penicillin-binding protein (PBP) 2?. READ MORE

5. 3. Water-swelling tablets based on hydrophobically modified poly(acrylic acid) - Effects of amphiphiles on swelling and drug release

   Author : Patrik Knöös; Fysikalisk kemi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Drug deliver; Controlled release; Hydrophobically modified polymers; Surfactant-polymer interactions; Poorly soluble drug;

   Abstract : An important issue within the pharmaceutical world today is the increasing number of poorly soluble drugs. These often show a low bioavailability and a susceptibility to varying conditions in the intestine. READ MORE

6. 4. Drug-resistant Mycobacterium tuberculosis in Estonia

   Author : Annika Krüüner; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Tuberculosis; Estonia; M. tuberculosis; drug resistance; MDR-TB; Beijing genotype; cross-resistance; kanamycin; amikacin; rrs mutations; 16S rRNA; exposure; nosocomial transmission; mycobacterial persistence; re-infection; DST; second-line drugs; Bactec; 460; DNA fingerprinting; spoligotyping;

   Abstract : Tuberculosis (TB) infection and disease patterns among different populations are extremely heterogeneous. This thesis explores mainly by microbiological methods the epidemiology of TB in Estonia. Through the work high rates of drug resistance were found. READ MORE

7. 5. Rapid assessment of drug susceptibility and mutation to resistance in mycobacterium tuberculosis Beijing type

   Author : Jim Werngren; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The increasing rates of multidrug resistant tuberculosis (MDR-TB) worldwide, are seriously threatening the TB control efforts. The present thesis was aimed at increasing the knowledge about the role of different factors, such as the development of drug resistance and the efficacy of drug susceptibility assessments, in the problem with MDR-TB. READ MORE