Search for dissertations about: "drug use"

Showing result 21 - 25 of 1134 swedish dissertations containing the words drug use.

  2. 21. Development and Evaluation of Lipodisks Intended for Use as Biomimetic Membranes and Drug Carriers

    Author : Malin Morin Zetterberg; Katarina Edwards; Jonas Bergquist; Ana Maria Carmona-Ribeiro; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; model membranes; drug delivery; drug partitioning; antimicrobial peptides; nanocarriers; cryo-TEM; polymer-stabilized bilayer disks; Chemistry with specialization in Physical Chemistry; Kemi med inriktning mot fysikalisk kemi;

    Abstract : Polyethylene glycol-stabilized lipodisks have emerged as a novel type of lipid-based nanoparticles with high potential as both drug carriers and biomimetic membranes. In this thesis we assess both of these applications, and show how the properties of the lipodisks can be further developed and optimized. READ MORE

  4. 22. Drug treatment in children with focus on off-label drug use

    Author : Elin Kimland; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Child; drug treatment; off-label; drug related problems; adverse drug reactions; drug labelling;

    Abstract : There is a lack of paediatric documentation concerning efficacy and safety of many drugs, which contribute to drug use outside the terms of the product license (off-label). In the present thesis, four studies (I-IV), using different settings and design to evaluate pharmacological treatment in children, with focus on off-label drug use, is presented. READ MORE

  5. 23. Cannabis use : understanding other illicit drug use, drug-related morbidity and dependence

    Author : Rynaz Rabiee; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Amid increased prevalence globally of both cannabis use, and cannabis use disorder (CUD), changes of the legal status of use, as well as increased cannabis potency, it is important to increase the understanding about the health effects from using this psychoactive substance. Improved understanding will provide better prerequisites when shaping policies and healthcare systems targeting affected individuals. READ MORE

  6. 24. Teenage Kicks – The Differential Development of Drug Use, Drunkenness, and Criminal Behaviour in Early to Mid-Adolescence

    Author : Russell Turner; Göteborgs universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Drug use; Drunkenness; Alcohol intoxication; Criminal behaviour; Delinquency; Adolescence; Adolescent development; Risk behaviour; Risk factor; Prevention; Critical realism; realist method; Person-oriented method;

    Abstract : This thesis studies the development of drug use, drunkenness, and criminal behaviour in early to mid-adolescence. Its main aims are to improve knowledge about how and why these three behaviours develop and to contribute towards the development of theory that can have applications in prevention policy and practice. The thesis comprises four studies. READ MORE

  7. 25. Pharmacokinetic, efficacy and safety modeling of new treatments against drug-resistant tuberculosis

    Author : Lénaïg Tanneau; Mats Karlsson; Elin Svensson; Italo Poggesi; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacokinetics; pharmacodynamics; pharmacometrics; nonlinear mixed effect models; tuberculosis; drug-resistance; bedaquiline; delamanid; metabolite; drug-drug interactions; QTc interval; transaminases; time-to-positivity; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : Tuberculosis (TB) is an ancient infectious disease that remains one of the greatest killers on the planet. Its eradication is impeded by the development of resistance to first-line treatment. Each year half a million patients are infected with drug-resistant (DR) TB. READ MORE