Search for dissertations about: "drugs"

Showing result 6 - 10 of 2448 swedish dissertations containing the word drugs.

  2. 6. LDI-MS strategies for analysis of polymer degradation products, additives and drugs

    Author : Nina Aminlashgari; Minna Hakkarainen; Peter J. Schoenmakers; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; laser desorption ionization-mass spectrometry LDI-MS ; surface; polymer degradation products; additive; drugs; nanoparticles; nanocomposites; Kemi; Chemistry;

    Abstract : The advancement of mass spectrometry (MS) has been and continues to be a prominent analytical technique for highly accurate determination of analytes. The goal of this thesis was to develop new laser desorption ionization-mass spectrometric (LDI-MS) methods for analysis of polymer degradation products, additives and drugs. READ MORE

  4. 7. Molecular Profiling and Imaging of Peptides, Proteins and Drugs in Biological Tissue using Mass Spectrometry

    Author : Anna Nilsson; Per E. Andrén; Garry Corthals; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; peptidomics; mass spectrometry; liquid chromatography; MALDI imaging; neuropeptides; drugs; brain; Pharmacology; Farmakologi;

    Abstract : Biological functions within cells and organisms are mainly carried out by the translational products; proteins and peptides. The analysis and characterization of these biomolecules are of great importance for the progress in disease research and biomarker and drug discovery. READ MORE

  5. 8. Analysis of drugs and proteins in biological matrices, using different types of sample preparations and mass spectrometry

    Author : Aljona Saleh; Ingrid Granelli; Jonas Bergquist; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bioanalysis; drugs; proteins; liquid chromatography; two-dimensional liquid chromatography; mass spectrometry; Analytical Chemistry; analytisk kemi;

    Abstract : This thesis describes bioanalysis of small and large molecules in biological matrices and includes screening of illegal drugs in urine with high resolution mass spectrometer, bioanalysis of MTH1 inhibitors in mice plasma and quantification of proteins in plasma and cell lysates.Screening of illegal drugs was based on high resolving power mass spectrometer (QTOF) and the results were compared to immunoassays. READ MORE

  6. 9. Discriminative control of behavior by drugs : a method to study subjective response characteristics to drugs in animals

    Author : Torbjörn Järbe; Uppsala universitet; []
    Keywords : SOCIAL SCIENCES; SAMHÄLLSVETENSKAP;

    Abstract : .... READ MORE

  7. 10. Characterisation of Aqueous Solutions, Liquid Crystals and Solid State of Non-ionic Polymers in Association with Amphiphiles and Drugs

    Author : Annika Ridell; Martin Malmsten; Sven Engström; David Attwood; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; polymer; surfactant; phase diagram; x-ray diffraction; fluorescence spectroscopy; calorimetry; PEG; cellulose ether; viscometry; cubic phase; liquid crystals; drugs; solid dispersion; Fysikalisk kemi; Physical chemistry; Fysikalisk kemi; Fysikalisk och oorganisk farmaceutisk kemi; Physical and Inorganic Pharmaceutical Chemistry;

    Abstract : Cellulose ethers and polyethylene glycols are used in drug formulations as water swelling or water soluble matrices. Polar lipids, for example monoglycerides, and surfactants can be used to solubilise hydrophobic or amphiphilic drugs and to formulate potential drug delivery vehicles such as emulsions, liposomes and cubic phases. READ MORE