Search for dissertations about: "dual activation"

Showing result 1 - 5 of 124 swedish dissertations containing the words dual activation.

  1. 1. Platelet activation and aggregation: Clinical and experimental studies

    Author : Sukhi Singh; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Platelet concentrate; Adrenaline; Noradrenaline; Ticagrelor; Platelet aggregation; Platelet activation;

    Abstract : Background: Dual antiplatelet therapy with acetylsalicylic acid (ASA) and the adenosine diphosphate (ADP)-receptor antagonist ticagrelor increases the risk of bleeding complications during cardiac surgery. The overall aim of this thesis was to identify and evaluate current and potential methods to reduce and prevent bleeding complications in patients with ongoing antiplatelet therapy. READ MORE

  2. 2. Development and Studies of the Processes Involved in Minor Enantiomer Recycling

    Author : Anna Laurell Nash; Christina Moberg; Karl Anker Jørgensen; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; asymmetric catalysis; biocatalysis; cyanohydrins; dual activation; Lewis acid; Lewis base; minor enantiomer recycling; recycling; titanium; Kemi; Chemistry;

    Abstract : This thesis describes the development and rationalization of processes involved in a new methodology developed in our group, minor enantiomer recycling.The first part of the thesis addresses mechanistic studies of one of the reactions involved in minor enantiomer recycling, dual Lewis acid-Lewis base catalyzed acetylcyanation of aldehydes. READ MORE

  3. 3. New Methods for Chiral Cyanohydrin Synthesis

    Author : Erica Wingstrand; Christina Moberg; Benjamin List; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; acyl cyanides; asymmetric synthesis; biocatalysis; cyanide; cyanohydrins; dual activation; enzymes; high-throughput screening; Lewis acid; Lewis base; metal catalysis; minor enantiomer recycling; salen; titanium; Chemistry; Kemi;

    Abstract : This thesis deals with method development in asymmetric catalysis and specifically syntheses of enantioenriched O-functionalized cyanohydrins. The first part describes the development of a method for the synthesis of O‑alkoxycarbonylated and O-acylated cyanohydrins. READ MORE

  4. 4. Strategies for controlling solid biomass conversion in dual fluidized bed gasifiers

    Author : Teresa Berdugo Vilches; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; char gasification; operating conditions; steam reforming; feldspar.; bauxite; segregation; olivine; in situ gas upgrading; ilmenite; dual fluidized bed; tar removal;

    Abstract : In the chemical industry, Synthesis Gas (syngas) has been traditionally produced by steam reforming of natural gas and naphtha. Steam gasification of biomass offers an alternative route for the production of syngas from renewable sources. READ MORE

  5. 5. Mechanisms of hedgehog signaling activation in cancer development

    Author : Mohammed Ferdous-Ur Rahman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Hedgehog (HH) signaling has an important role in many physiological processes, and deregulation of this pathway can result in a wide range of malignancies. The aim of this thesis is to identify and evaluate the role of various posttranscriptional mechanisms, including alternative splicing, RNA editing and antisense RNAs, associated with different key components of HH signaling. READ MORE