Search for dissertations about: "dual structure of science"

Showing result 1 - 5 of 53 swedish dissertations containing the words dual structure of science.

  1. 1. Structure-based Virtual Screening for Ligands of G Protein-coupled Receptors : Design of Allosteric and Dual-Target Modulators

    Author : Stefanie Kampen; Jens Carlsson; Peter Kolb; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; G protein-coupled receptors; Polypharmacology; Molecular Docking; Structure-based Drug Design; Parkinson’s Disease; Virtual Screening; Allosteric Modulators; Bioinformatics; Bioinformatik;

    Abstract : G protein-coupled receptors (GPCRs) are integral membrane proteins responsible for signal transduction of extracellular stimuli into the cell. Because of their widespread distribution throughout the human body and important roles in physiological processes, GPCRs are prominent drug targets and approximately 34% of all approved drugs interact with members of this superfamily. READ MORE

  2. 2. A Structure Utilizing Inexact : Primal-Dual Interior-Point Method for Analysis of Linear Differential Inclusions

    Author : Janne Harju Johansson; Anders Hansson; Ulf Jönsson; Linköpings universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Automatic control; Optimization; systems theory; Automatic control; Reglerteknik;

    Abstract : The ability to analyze system properties for large scale systems is an important part of modern engineering. Although computer power increases constantly, there is still need to develop tailored methods that are able to handle large scale systems, since sometimes standard methods cannot handle the large scale problems that occur. READ MORE

  3. 3. Investigations into Information Semantics and Ethics of Computing

    Author : Gordana Dodig-Crnkovic; Björn Lisper; Lars-Göran Johansson; Jan Gustafsson; Luciano Floridi; Mälardalens högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Computing and Philosophy; Philosophy of Computing; Philosophy of Information; Computer science; Datavetenskap; Computer Science; datavetenskap;

    Abstract : The recent development of the research field of Computing and Philosophy has triggered investigations into the theoretical foundations of computing and information.This thesis consists of two parts which are the result of studies in two areas of Philosophy of Computing (PC) and Philosophy of Information (PI) regarding the production of meaning (semantics) and the value system with applications (ethics). READ MORE

  4. 4. Materials Science of Multilayer X-ray Mirrors

    Author : Naureen Ghafoor; Jens Birch; Claude Montcalm; Linköpings universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Soft X-rays; Multilayer mirrors; Magnetron sputtering; Interface engineering; Materials science; Teknisk materialvetenskap;

    Abstract : This thesis treats the reflective and structural properties of multilayer structures. Soft X-ray multilayer mirrors intended as near-normal incidence reflective optics and polarizers in the water window (λ=2.4-4.4 nm) are the main focus. READ MORE

  5. 5. Structural and Functional Studies of Wilms Tumour Protein - WT1; Novel Insights into Functionality of Zinc Finger Proteins

    Author : Elmar Nurmemmedov; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Naturvetenskap; Natural science; function; structure; transcription factor; cancer; affinity; kinetics; Biacore; RNA binding; DNA binding; Wilms tumour WT1 ; zinc finger;

    Abstract : The molecular process under which message in DNA is relayed onto RNA is called transcription, and it accomplished through involvement of so-called transcription factors. Zinc finger proteins are one of the most abundant classes of regulatory proteins in eukaryotic cells where they play central roles in a variety of cellular activities. READ MORE