Search for dissertations about: "dynamic systemic resolution"

Found 5 swedish dissertations containing the words dynamic systemic resolution.

  2. 1. Chemoenzymatic Resolution in Dynamic Systems : Screening, Classification and Asymmetric Synthesis

    Author : Yan Zhang; Olof Ramström; Sabine Flitsch; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; constitutional dynamic chemistry; dynamic systemic resolution; dynamic kinetic resolution; enzyme catalysis; transesterification; enzyme promiscuity; asymmetric synthesis; pattern recognition; self-inhibition.;

    Abstract : This  thesis  is  divided  into  four  parts,  all  centered  around  Constitutional Dynamic  Chemistry  (CDC)  and  Dynamic  Kinetic  Resolution  (DKR)  using biocatalysts for selective transformations, and their applications in screening of bioactive compounds, organic synthesis, and enzyme classification.   In  part  one,  an  introduction  to  CDC  and  DKR  is  presented,  illustrating  the basic  concepts,  practical  considerations  and  potential  applications  of  such dynamic systems, thus providing the background information for the studies in the following chapters. READ MORE

  4. 2. Catalysis in Dynamic Systems: Control within Molecular Reaction Networks

    Author : Fredrik Schaufelberger; Olof Ramström; Leonard Prins; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; systems chemistry; dynamic covalent chemistry; catalyst screening; reaction networks; organocatalysis; imine exchange; combinatorial chemistry; dynamic systemic resolution; feedback; error-correction; Morita-Baylis-Hillman reaction; C-H activation; H-bond catalysis; transamination; Kemi; Chemistry;

    Abstract : Life as we know it is based on complex networks of biochemical reactions that constantly interact within large dynamic systems. The field of systems chemistry uses chemical models to study how reaction networks – and thereby life – function on a molecular level. READ MORE

  5. 3. Resolution of Dynamic Systems: Applications in Asymmetric Synthesis and Materials Science

    Author : Lei Hu; Olof Ramström; Douglas Philp; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Kemi; Chemistry;

    Abstract : This thesis is built on the concepts of constitutional dynamic chemistry and dynamic kinetic resolution, where reversible covalent reactions are used to generate dynamics and kinetically controlled reactions are employed for resolution. The thesis is divided into two parts:The first section focuses on the study of dynamic systemic resolution, a concept derived from constitutional dynamic chemistry. READ MORE

  6. 4. Tissue microbiology : an integrated approach for intravital studies of host-pathogen interactions

    Author : Ferdinand Xiankeng Choong; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : A bacteria infection in the living host is the summation of a myriad of interactions. Reductionistic and sacrificial experiment models cannot replicate this complexity. The Tissue Microbiology approach overcomes this by allowing the live host and pathogen to control all facets of the infection model. READ MORE

  7. 5. Hip fractures : A biomechanical analysis of fracture strength prediction, prevention, and repair

    Author : Joeri Kok; Avdelningen för Biomedicinsk teknik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Finite element; Bone cement; Femur; Fracture; Experimental mechanics; X-ray imaging;

    Abstract : Due to the aging population, hip fracture incidence has been increasing over the past decades. Measurements of bone mineral density with dual energy X-ray absorptiometry are the gold standard for hip fracture risk assessment, where patients with a low bone density have a high risk of fracture. READ MORE