Search for dissertations about: "dynamic allele-specific hybridization"
Showing result 1 - 5 of 8 swedish dissertations containing the words dynamic allele-specific hybridization.
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1. Microfluidic bead-based methods for DNA analysis
Abstract : With the completion of the human genome sequencing project, attention is currently shifting toward understanding how genetic variation, such as single nucleotide polymorphism (SNP), leads to disease. To identify, understand, and control biological mechanisms of living organisms, the enormous amounts of accumulated sequence information must be coupled to faster, cheaper, and more powerful technologies for DNA, RNA, and protein analysis. READ MORE
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2. Technology development for genome and polymorphism analysis
Abstract : Single nucleotide polymorphism (SNP) is widely expected to provide a multitude of benefits in areas of medical research. There is, however, a growing disparity between the rate of SNP discovery and the development of effective technologies for large scale SNP scoring. READ MORE
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3. SNP technology and Alzheimer’s disease
Abstract : One major goal of genetic research is to understand the role of genetic variation. By far the most common type of such variation in humans involves single DNA bases, and is termed single nucleotide polymorphism (SNP). READ MORE
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4. Assembly of microsystems for optical and fluidic applications
Abstract : This thesis addresses assembly issues encountered in optical and fluidic microsystem applications. In optics, the first subject concerns the active alignment of components in optical fibersystems. READ MORE
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5. Functional genetics of the interleukin-4 receptors in allergic asthma
Abstract : Asthma is a complex disorder, with both genetic and environmental factors contributing to disease development. Our aim was to analyse possible associations between genetic variations of immunologically important genes and the susceptibility to and severity of allergic asthma in adults. READ MORE