Search for dissertations about: "dynamin"

Showing result 6 - 10 of 18 swedish dissertations containing the word dynamin.

  1. 6. The role of multifunctional scaffolding proteins in the synaptic vesicle cycle

    Author : Wei Jiao; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Fast synaptic transmission occurs at specialized junctions between neurons referred to as chemical synapses. Action potentials induce an influx of calcium ions into presynaptic terminals, which contain neurotransmitter-filled synaptic vesicles (SVs), triggering fusion of the vesicles with the plasma membrane and resulting in the release of neurotransmitters. READ MORE

  2. 7. Molecular mechanisms in synaptic vesicle recycling

    Author : Joel Jakobsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Neurons communicate through specialized contacts called synapses, which consist of pre- and postsynaptic compartments separated by a narrow synaptic cleft. The stimulus- dependent rapid influx of calcium ions into the presynaptic compartment induces fusion of neurotransmitter-filled vesicles with the plasma membrane and release of their content into the synaptic cleft. READ MORE

  3. 8. Membrane-remodeling by SNX18 in endosomal transport and autophagy

    Author : Karin Håberg; Sven Carlsson; Geir Bjørkøy; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sorting nexin; SNX9-family; SNX18; endosomal transport; autophagy; medicinsk biokemi; Medical Biochemistry;

    Abstract : The intracellular space of eukaryotic cells is subdivided into functionally distinct membrane-enclosed organelles. Regulation of these intracellular membranes requires an intricate network of specialized lipids and proteins that maintain organellar integrity and mediate transport between organelles. READ MORE

  4. 9. Dissecting sterol function during clathrin-dependent endocytosis and cytokinesis in Arabidopsis thaliana

    Author : Márcia Frescatada-Rosa; Markus Grebe; Wolfgang Lukowitz; Umeå universitet; []
    Keywords : Arabidopsis; membrane; sterols; cytokinesis; KNOLLE; endocytosis; clathrin; DRP1A; Developmental Biology; miljömedicinsk utvecklingsbiologi; molekylärbiologi; Molecular Biology; molecular cell biology; molekylär cellbiologi;

    Abstract : Sterols are lipid components of eukaryotic membranes. Alterations of membrane sterol composition perturb the execution of cell division, which in diverse eukaryotes can have severe consequences for development of the organism. Partitioning of the cytoplasm during cell division occurs at the final stage of cell division named cytokinesis. READ MORE

  5. 10. Cellular Uptake of Amyloid Forming Proteins Related to Neurodegenerative Disease

    Author : Emelie Vilhelmsson Wesén; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aβ 1-40 ; flow cytometry; confocal microscopy; SH-SY5Y; fluorescence; Aβ 1-42 ; Alzheimer’s disease; amyloid fibril; α-synuclein; amyloid-β;

    Abstract : Aggregation and deposition of disease-associated protein is a pathological hallmark of several human disorders, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). These diseases are characterized by the formation of amyloid-β (Aβ) and α-synuclein (α-syn) amyloid fibrils, in extracellular and intracellular locations, respectively. READ MORE