Search for dissertations about: "dyslipidaemia"

Showing result 1 - 5 of 27 swedish dissertations containing the word dyslipidaemia.

  1. 1. Modelling of tolerance and rebound in normal and diseased rats

    Author : Christine Ahlström; Göteborgs universitet.; Gothenburg University.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; feedback modelling; tolerance; rebound; pharmacokinetics; pharmacodynamics; dyslipidaemia; nicotinic acid; non-esterified fatty acids;

    Abstract : The development of rebound and tolerance is an important consideration when optimizing medical therapy, both with respect to drug dosing and adverse effects. By using quantitative approaches to study these processes, potential risks can be minimized. READ MORE

  2. 2. Genetic Determinants of Dyslipidemia

    University dissertation from Lund University, Faculty of Medicine

    Author : Tibor V Varga; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetic epidemiology; Genetic polymorphism; dyslipidaemia; Cholesterol; Triglyceride; Genetic risk; genetic risk score; Single nucleotide polymorphism; Prediction; Gene-environment interactions; Randomized controlled trial; prospective cohort studies; Observational study; GLACIER Study; Diabetes Prevention Program;

    Abstract : Dyslipidemia is a chronic deviation from normal blood lipid levels that can lead to atherosclerosis and other cardiovascular diseases; dyslipidemia and its sequelae are caused by the complex interplay of genetic and environmental factors. Although circulating concentrations of total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (LDL-C) have a strong genetic underpinning, not much is known about the genetic factors that affect long-term deteriorations in lipid concentrations. READ MORE

  3. 3. Insights into the relationship between coronary calcification and atherosclerosis risk factors

    University dissertation from Umeå : Umeå University

    Author : Rachel Nicoll; Umeå universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Coronary artery calcification; risk factors; atherosclerosis; stenosis; Cardiology; kardiologi;

    Abstract : Introduction Coronary artery disease (CAD) is the most common cause of death in Europe and North America and early detection of atherosclerosis is a clinical priority. Diagnosis of CAD remains conventional angiography, although recent technology has introduced non-invasive imaging of coronary arteries using computed tomographic coronary angiography (CTCA), which enables the detection and quantification of coronary artery calcification (CAC). READ MORE

  4. 4. Screening strategies for dysglycaemia in relation to cardiovascular risk

    University dissertation from Stockholm : Karolinska Institutet, Dept of Medicine, Solna

    Author : Bahira Shahim; Karolinska Institutet.; Karolinska Institutet.; [2019]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Background: Dysglycaemia, defined as type 2 diabetes (T2DM) or impaired glucose tolerance (IGT), is a major risk factor for cardiovascular disease (CVD). Dysglycaemia and CVD together account for more than half of worldwide mortality. READ MORE

  5. 5. Risk factors for development of neurocognitive disorders

    University dissertation from Lund University, Faculty of Medicine

    Author : Anna-Märta Gustavsson; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2019]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vascular risk factors; dementia; Alzheimer’s disease; ß-amyloid; white matter hyperintensities; cerebral small vessel disease;

    Abstract : AbstractVascular risk factors are believed to be involved in dementia development by increasing risk of the most common dementia types, Alzheimer’s disease (AD) and vascular dementia. The aim of this thesis was to study if risk factorsaffect key brain pathology directly, by using biomarkers for dementia in preclinical stages, and to assess previous findings in a large population-based setting. READ MORE