Search for dissertations about: "eNOS"
Showing result 6 - 10 of 45 swedish dissertations containing the word eNOS.
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6. Cardioprotective mechanisms by inhibition of the HMG-CoA reductase pathway and stimulation of peroxisome proliferator-activated receptors in myocardial ischaemia-reperfusion
Abstract : Acute myocardial ischaemia causes metabolic changes and results in a rapid decrease in the energy available to the cell. This leads to cell injury that, depending on the length of the ischaemic time, is reversible or irreversible. READ MORE
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7. Role of GLP-1 receptor agonists in endothelial function
Abstract : BACKGROUND: The leading cause of death for patients suffering from type 2 diabetes is macrovascular disease. Endothelial dysfunction is one of the earliest events identified in the pathogenesis of atherosclerosis. Hence, there is a need for finding glucose-lowering agents that cause direct positive effects on vasculature in diabetic patients. READ MORE
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8. Clinical and pathogenic aspects of otitis media
Abstract : One study on clinical treatment strategies in otitis media and two studies elucidating immunological events in otitis media in vitro, were conducted and joined in this thesis. First, topical treatment with or without systemic antibiotics against tube associated otorrhea in children with recurrent acute otitis media was evaluated. READ MORE
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9. On certain genetic and metabolic risk factors for carotid stenosis and stroke
Abstract : The present study evaluated genetic and metabolic factors influencing the risk of acute cerebrovascular disease (CVD) and internal carotid artery stenosis (ICA stenosis) in a Swedish community. The threonine (T) containing protein of the FABP2 A54T gene polymorphism has a greater affinity for long chain fatty acids (FFAs) than the alanine (A) containing protein. READ MORE
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10. NADPH oxidase and xanthine oxidoreductase as targets and regulators of the nitrate-nitrite-nitric oxide pathway
Abstract : Overproduction of reactive oxygen species (ROS) by NADPH oxidase (NOX) and xanthine oxidoreductase (XOR) with a concomitant decrease in the bioavailability of nitric oxide (NO) from eNOS contributes to the development of cardiovascular and metabolic disorders. Extensive research has proven the existence of an alternative NOS-independent pathway for NO production. READ MORE