Search for dissertations about: "eQTL"
Showing result 1 - 5 of 16 swedish dissertations containing the word eQTL.
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1. Domestication Effects on the Stress Response in Chickens : Genetics, Physiology, and Behaviour
Abstract : Animal domestication, the process where animals become adapted to living in proximity to humans, is associated with the alteration of multiple traits, including decreased fearfulness and stress response. With an estimated population of 50 billion, the domesticated chicken is the most populous avian species in the world. READ MORE
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2. eQTL mapping and inherited risk enrichment analysis : a systems biology approach for coronary artery disease
Abstract : Despite extensive research during the last decades, coronary artery disease (CAD) remains the number one cause of death, responsible for near 50% of global mortal- ity. A main reason for this is that CAD has a complex inheritance and etiology that unlike rare single gene disorders cannot fully be understood from studies of of genes one-by-one. READ MORE
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3. Quantitative genetics of gene expression and methylation in the chicken
Abstract : In quantitative genetics the relationship between genetic and phenotypic variation is investigated. The identification of these variants can bring improvements to selective breeding, allow for transgenic techniques to be applied in agricultural settings and assess the risk of polygenic diseases. READ MORE
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4. Functional epigenetic analyses in the context of psychiatric health in adolescence
Abstract : Adolescence is a unique and formative period for learning and developing skills and abilities for adulthood. The prevalence of mental health problems in adolescents is estimated to 10-20%, being a major risk for suicide, social and academic impairments. Suicide is the third leading cause of death in older adolescents (15-19 years). READ MORE
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5. Functional genomics approaches to dissect causal DNA variations in obesity and type 2 diabetes
Abstract : GWAS studies have identified hundreds of loci that associate with obesity and type 2 diabetes. However, the functional relevance of the genetic variants, and their impact on disease or traits, is largely unknown. READ MORE