Search for dissertations about: "early B-cell factor 1 EBF1"

Found 4 swedish dissertations containing the words early B-cell factor 1 EBF1.

  2. 1. To be or not to be, unraveling molecular mechanisms for lineage decisions in developing blood cells

    Author : Robert Månsson; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellular fluids; Haematology; common lymphoid precursor CLP ; early B-cell factor 1 EBF1 ; B-cell; Stemcell; hematopoiesis; extracellulära vätskor; Immunology; serology; transplantation; Immunologi; serologi;

    Abstract : All hematopoietic cells originate from hematopoietic stem cells (HSC) residing in the BM. The process of differentiation, through which HSCs generate progenitors and subsequently mature blood cells has been extensively studied but many of the regulatory mechanisms involved remains elusive. READ MORE

  4. 2. The regulatory role of microRNA in human adipocytes and their link to insulin resistance

    Author : Yasmina Belarbi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : White adipose tissue (WAT) is a highly plastic organ which secretes a large number of peptide factors termed adipokines. Increased caloric intake increases WAT mass which results in marked alterations in the secretory pattern. This may be mediated via both transcriptional and post-transcriptional mechanisms. READ MORE

  5. 3. Identification of novel factors regulating human adipocyte function and their link to metabolic health

    Author : Paul Petrus; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The white adipose tissue (WAT) regulates energy homeostasis by storing and releasing energy in the form of fat as well as functioning as an endocrine organ secreting a myriad of different peptides. The heterogeneous WAT consists of various cell types including the lipid-storing cells termed adipocytes. READ MORE

  6. 4. Pathophysiological mechanisms and clinical manifestations in primary Sjögren’s syndrome and Systemic lupus erythematosus (SLE)

    Author : Marika Kvarnström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Primary Sjögren’s syndrome (pSS) is a systemic inflammatory autoimmune condition. The etiology of pSS is mainly unknown, but it has been suggested that environmental factors trigger an immune response in genetically susceptible individuals. READ MORE