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Showing result 1 - 5 of 6 swedish dissertations matching the above criteria.

2. 1. Microbial and maternal influences on allergic sensitization during childhood: defining a role for monocytes

   Author : Shanie Saghafian Hedengren; Eva Sverremark-Ekström; Susan Prescott; Stockholms universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Monocytes; allergic sensitization; maternal allergy; Toll-like receptor; p38-MAPK; IL-6; Epstein-Barr virus; early-life microbial exposure; NK cells; IFN-γ; Immunology; Immunologi; immunologi; Immunology;

   Abstract : Allergic diseases are influenced by genetics and the environment. Maternal allergy appears to confer a higher risk for allergic sensitization than paternal allergy, suggesting an in utero influence. READ MORE

4. 2. The Gut Bacterial Flora - Focus on Early Life and Physiological Traits

   Author : Caroline Linninge; Avdelningen för livsmedel och läkemedel; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gut microbiota; atopic eczema; inflammation; bacterial diversity; Escherichia coli; Lactobacillus plantarum; molecular-genetic methods;

   Abstract : The gastrointestinal tract of the foetus is considered sterile but during vaginal birth the neonate comes into contact with bacteria from the maternal vaginal and intestinal microbiota. The main focus of this doctoral thesis was to elucidate the initial bacterial ecosystem in newborns and to relate microbial perturbations to physiological traits. READ MORE

5. 3. Early-life gut microbiota and breast milk oligosaccharides in relation to childhood immune maturation and allergy

   Author : Ylva Margareta Sjögren; Eva Sverremark-Ekström; Outi Vaarala; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; allergy; infant; gut microbiota; human milk oligosaccharides; Bifidobacterium; Lactobacillus; Bacteroides fragilis; Clostridium difficile; family size; secretory IgA; toll like receptor; Immunology; Immunologi; immunologi; Immunology;

   Abstract : Atopic allergy is the most common chronic disease among children in the developed world. This high prevalence could be associated with low microbial exposure. The early gut microbiota appears to be important for immune maturation. READ MORE

6. 4. Pregnancy—A Critical Time for Mental Health : Interrogating Psychiatry with Microbiota-Gut-Brain Axis and Autonomic Nervous System Biomarkers

   Author : Mary C. Kimmel; Alkistis Skalkidou; Janet Cunningham; Emma Fransson; Samantha Meltzer-Brody; Susan Garthus-Niegel; Uppsala universitet; []
   Keywords : pregnancy; heart rate variability HRV ; microbiome; depression; anxiety; self-efficacy; cytokines; biomarkers;

   Abstract : Perinatal mood and anxiety disorders (PMADs) are common and impact the parent and child beyond the perinatal period of pregnancy and postpartum. The aim of this thesis was to study biomarkers that might reflect perinatal mental health. READ MORE

7. 5. Understanding allergies : how infections affect the function of T helper cells

   Author : Junjie Ma; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Allergic disorders are caused by a combination of hereditary and environmental factors. The hygiene hypothesis postulates that early-life microbial exposures impede the development of subsequent allergic diseases. However, unambiguous evidence that microbes reduce the development of allergic disorders is still lacking. READ MORE