Search for dissertations about: "effects of obesity in brain"

Showing result 1 - 5 of 31 swedish dissertations containing the words effects of obesity in brain.

  2. 1. Obesity Genetics : Functional Aspects of Four Genetic Loci Associated with Obesity and Body Mass

    Author : Mathias Rask-Andersen; Helgi Schiöth; Ingrid Dahlman; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Obesity is a complex disorder which has reached epidemic proportions in many parts of the world. Twin studies have demonstrated a high heritability for obesity. The subsequent appli-cation of genome wide association studies (GWAS) in the last decade have identified at least 32 genetic loci associated with body mass and obesity. READ MORE

  4. 2. Neuroinflammation in Alzheimer’s disease and obesity

    Author : Linda Tracy; Kerstin Iverfeldt; Colin Combs; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Alzheimer s disease; obesity; neuroinflammation; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : Alzheimer’s disease (AD) and obesity are both major problems in the western world. Although they may appear to have little in common at first glance, they are both characterized by chronic inflammation. Exactly how inflammation affects these disorders is far from clear. READ MORE

  5. 3. Brain function and glucocorticoids in obesity and type 2 diabetes including effects of lifestyle interventions

    Author : Andreas Stomby; Tommy Olsson; Mats Ryberg; Carl-Johan Boraxbekk; Alasdair MacLullich; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; type 2 diabetes; glucocorticoid; cortisol; 11beta hydroxysteroid dehydrogenase type 1; episodic memory; functional magnetic resonance imaging; paleolithic diet; exercise; Internal Medicine; invärtesmedicin; medicin; Medicine;

    Abstract : Background Obesity and associated metabolic dysregulation are linked to impaired cognitive function and alterations in brain structure, which increases the risk of age-related dementia. Increased glucocorticoid (GC) exposure may be a potential mediator of these negative effects on the brain. READ MORE

  6. 4. The psycho-metabolic consequences of sleep loss in people

    Author : Lieve T. van Egmond; Christian Benedict; Veronica Witte; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sleep; nutrition; metabolism; sleep deprivation; sex differences; weight differences; obesity; cognition; mediterranean diet; brain health; social evaluation; night work; occupational performance; emotion; vigilance; energy balance; diet; elderly; Fysiologi; Physiology; Nutrition; Nutrition; Neurology; Neurologi; Psychiatry; Psykiatri; Geriatrics; Geriatrik; Medicinsk vetenskap; Medical Science;

    Abstract : Night work is vital for maintaining our 24/7 society; however, in the long run, it may have adverse health consequences like obesity and Alzheimer’s disease. By performing one of the most extensive experimental in-laboratory studies to date, I sought to investigate how sleep deprivation impacts important features like how a person responds to others and how well a person can sustain attention and wakefulness during simulated night work. READ MORE

  7. 5. Experimental Traumatic Brain Injury and Cell Death - in vivo and in vitro aspects

    Author : Gustav Mattiasson; Sektion IV; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurofysiologi; neuropsychology; Neurology; uncoupling protein; mitochondrial permeability transition; cerebral blood flow; functional outcome; cell death; mitochondria; hippocampus; preconditioning; trauma; Brain; ischemia; neuropsykologi; Neurologi; neurophysiology;

    Abstract : Traumatic and ischemic brain damage are major causes of disability and death. While much effort has been spent on developing pharmacological treatments for these conditions, no neuroprotective drugs are in clinical use. READ MORE