Search for dissertations about: "eicosanoid"

Showing result 6 - 10 of 38 swedish dissertations containing the word eicosanoid.

  2. 6. Studies on a novel cytosolic/nuclear binding protein for the eicosanoid 12(S)-hydroxyeicosatetraenoic acid

    Author : Helena Herbertsson; Örjan Wrange; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Hydroxyeicosatetraenoic acids (HETEs) are lipoxygenase metabolites of arachidonic acid. HETEs were long considered to have few or no important biological function - a view that proved to be incorrect. READ MORE

  4. 7. Mast cell activation in response to osmotic and immunological stimulation with focus on release of eicosanoid mediators

    Author : Magdalena Gulliksson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Exercise-induced bronchoconstriction; cyclooxygenase; cord blood derived mast cells; mannitol; prostaglandin D2; leukotriene C4; leukotriene E4; histamine and 15-lipoxygenase.;

    Abstract : Mast cells are important in asthma and other inflammatory diseases. Subjects with asthma have been found to have an increased number of mast cells in their airway smooth muscle and this was related to airway sensitivity. READ MORE

  5. 8. Quantification of inflammatory mediators to explore molecular mechanisms and sub-phenotypes of asthma

    Author : Johan Kolmert; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : This thesis summarizes a series of studies using liquid chromatography coupled to mass spectrometry methodologies to quantify metabolites of fatty acids (i.e. READ MORE

  6. 9. Antimicrobial peptides and eicosanoids : roles and interactions in inflammation and host defense

    Author : Xiao Tang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Antimicrobial peptides (AMPs) have a broad spectrum of activities and exert their functions by both direct killing of microbes through the interaction with the microbial membrane, and modulation of innate and adaptive immunity of the host. In humans, cathelicidins and defensins represent the major families of AMPs. READ MORE

  7. 10. Identification of natural activators of the nuclear receptor peroxisome proliferator-activated receptor : relevance to the pathogenesis of atherosclerosis

    Author : Jane Wigren; Ernst Oliw; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Polyunsaturated fatty acids induce peroxisome proliferation. This phenomenon is mediated by the ligand-dependent transcription factor peroxisome proliferator-activated receptor (PPAR). This thesis is an investigation on the role of eicosanoids and oxidized products of linoleic acid for the activation of PPARs. READ MORE