Search for dissertations about: "elderly diabetes"

Showing result 1 - 5 of 77 swedish dissertations containing the words elderly diabetes.

  2. 1. The role of genetic variation and DNA methylation in human glucose metabolism and type 2 diabetes

    Author : Tina Rönn; diabetes och endokrinologi Genomik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gene expression; oxidative phosphorylation; GWAS; SNP; DNA methylation; epigenetics; type 2 diabetes;

    Abstract : The incidence of diabetes is increasing worldwide, with the most prevalent form being type 2 diabetes. Two fundamental processes contribute to the development of type 2 diabetes: insulin resistance in target organs and insufficient insulin secretion from the pancreatic beta-cells. READ MORE

  4. 2. Exploring the Grey Zone between Type 1 and Type 2 Diabetes

    Author : Ekaterine Bakhtadze; diabetes och endokrinologi Genomik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : T1D is most common in children and young adults and is characterized by autoimmune destruction of insulin producing pancreatic beta cells, presence of certain risk genotypes such as HLA-DQB1, INS VNTR, PTPN22 and need of insulin for survival. In adults the same situation is often referred to as Latent Autoimmune Diabetes in Adults (LADA), with age at onset after 35 years and non-insulin requiring at least for 6 month after diagnosis. READ MORE

  5. 3. Role of Proneurotensin in Cardiometabolic Diseases

    Author : Ayesha Fawad; Kardiovaskulär forskning - hypertoni; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine and Health Sciences; Cardiometabolic disease; Obesity : complications; Diabetes; type 2; Proneurotensin; Dyslipidemia;

    Abstract : The burden of cardiometabolic diseases is increasing worldwide. Early detection of high-risk individuals is essential for appropriate diagnosis, better treatment outcomes, quality of life and lower health related costs. READ MORE

  6. 4. Glucagon Counter-Regulation to Hypoglycemia During Incretin-Based Therapy

    Author : Johan Farngren; Lund Medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Incretin; DPP-4; GLP-1; Glucagon; Hypoglycemia; Diabetes;

    Abstract : Incretin-based therapy is associated with low risk of hypoglycemia in type 2 diabetes mellitus (T2DM) possibly due to its glucose-dependency in stimulating insulin secretion and a sustained glucagon response during hypoglycemia. This is of special relevance when it is combined with insulin or given to elderly patients since both insulin therapy and high age are associated with impaired glucagon counter-regulation. READ MORE

  7. 5. Register-based evaluation of primary care - Focus on chronic disease

    Author : Helena Ödesjö; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cardiovascular diseases; diabetes; elderly; health care quality assurance; hypertension; incentive; nurses; pay för performance; potentially inappropriate medication list; primary health care; secondary prevention; statins; Sweden; quality indicators;

    Abstract : Background: Options for following up primary care at the regional level have increased in Sweden, partly as a result of a national reform in 2009. In Region Västra Götaland (VGR) this was the starting point for a quality initiative with about 100 indicators, using extensive healthcare registers. READ MORE