Search for dissertations about: "electrospray ionization mass spectrometry ESIMS"

Found 4 swedish dissertations containing the words electrospray ionization mass spectrometry ESIMS.

  2. 1. Tools for applied soft ionization mass spectrometry

    Author : Joakim Romson; Åsa Emmer; Peter Dinér; Steven Wilson; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mass spectrometry; Electrospray ionization; Matrix assisted laser desorption ionization; Mass accuracy; Mass shifts; Ion trap; Capillary electrophoresis; Sample concentration; Masspektrometri; Elektrospray-jonisering; Matrisassisterad laser desorbtion jonisering; Mass-exakthet; Masskift; Jonfälla; Kapillärelektrofores; Provkoncentration; Kemi; Chemistry;

    Abstract :  Mass spectrometry (MS) is an important analytical tool. Its most importantadvantages are sensitivity, resolution, and accurate and precise m/zmeasurements. To get the best results from an instrument, the user musthave knowledge of its limitation and requirements. READ MORE

  4. 2. Advances in analytical methodologies for studies of the platinum metallome in malignant cells exposed to cisplatin

    Author : Yvonne Nygren; Erik Björn; Knut Irgum; Bente Gammelgaard; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Method development; Metallome; Inductively coupled plasma mass spectrometry; Electrospray ionization mass spectrometry; Liquid chromatography; Hyphenation; Organic modifier; Cisplatin; Platinum; Analytical chemistry; Analytisk kemi; analytisk kemi; Analytical Chemistry;

    Abstract : The scientific progress about the important chemotherapeutic drug substance cisplatin (CDDP) and its function has often been rendered by data difficult to interpret, and still many questions about its mode of action remains to be clarified by the scientific community. However, studies of CDDP possess a high complexity due to; i) low intracellular concentration, ii) many potential biomolecule targets, iii) poor or unknown stability of the intact drug and its biomolecule adducts and iv) complex and varying sample matrices. READ MORE

  5. 3. Hydroxamate Siderophores and Low Molecular Mass Organic Acids in Terrestrial and Aquatic Environments Determined by Liquid Chromatography Mass Spectrometry

    Author : Sofia Essén; Ulla Lundström; Dan Bylund; Mittuniversitetet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chemistry; Kemi;

    Abstract : Siderophores are low molecular mass organic compounds with high iron(III) stability constants. They are produced by many microorganisms, often in combination with low molecular mass organic acids (LMMOAs). Both siderophores and LMMOAs accelerate mineral weathering, thereby enhancing mineral nutrient availability. READ MORE

  6. 4. The structural diversity of lipopolysaccharides expressed by genetically defined clinical isolates of nontypeable Haemophilus influenzae

    Author : Martin Månsson; Elke K. H. Schweda; Jane Thomas-Oats; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Nontypeable Haemophilus influenzae NTHi ; lipopolysaccharide LPS ; nuclear magnetic resonance NMR spectroscopy; electrospray ionization mass spectrometry ESIMS ; structural analysis.;

    Abstract : Nontypeable Haemophilus influenzae (NTHi) is an important cause of otitis media and respiratory tract infections. Its lipopolysaccharide (LPS) molecule, an outer membrane component, is a major virulence factor of NTHi. The LPS molecule may also be an efficient target for antibodies which might be protective against NTHi disease. READ MORE