Search for dissertations about: "elfving"

Showing result 1 - 5 of 15 swedish dissertations containing the word elfving.

  1. 1. Transcriptional regulation of mouse ribonucleotide reductase

    Author : Anna Elfving; Lars Thelander; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ribonucleotide reductase; promoters; cell cycle; transcriptional regulation; primer extension; protein purification; EMSA; Biochemistry; Biokemi; medicinsk biokemi; Medical Biochemistry;

    Abstract : All living organisms are made of cells and they store their hereditary information in the form of double stranded DNA. In all organisms DNA replication and repair is essential for cell division and cell survival. These processes require deoxyribonucleotides (dNTPs), the building blocks of DNA. READ MORE

  2. 2. Lumbar muscle fatigue and recovery : evaluation of electromyography in patients with long-term low-back pain and in healthy subjects

    Author : Britt Elfving; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Disability; electromyography; exponential; force level; gender; healthy subjects; interelectrode distance; low-back pain; erector spinae; maximal voluntary contraction; muscle fatigue; recovery; reliability; validity.;

    Abstract : Background: Lumbar muscle function is considered to be an important component of longterm low- back pain. The change in the median frequency of the power spectrum of the electromyographic (EMG) signal is commonly used to estimate muscle fatigue. READ MORE

  3. 3. Improving the diagnostic armamentarium of lung cancer

    Author : Hedvig Elfving; Patrick Micke; Fredrik Pontén; Marika Nestor; Reinhard Büttner; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lung cancer; tissue microarray; immunohistochemistry; targeted therapy; immunotherapy; checkpoint inhibitors; immune microenvironment; prognosis; biomarkers; immune cells.;

    Abstract : Lung cancer is the leading cause of cancer-related death globally, with non-small cell lung cancer (NSCLC) constituting 85% of cases. The introduction of immunotherapies and targeted therapies have dramatically improved the prognosis and outcome for a subset of patients, and stressed the development of diagnostic tools for effective patient selection. READ MORE

  4. 4. Acute febrile illness in preschool children in Zanzibar - Infectious aetiologies, diagnosis and treatment

    Author : Kristina Elfving; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Children; Infections; Low-income country; Tanzania; malaria; pneumonia; antibiotics; fever; diagnosis; polymerase chain reaction; preschool; influenza virus; Respiratory syncytial virus; diarrhoea; norovirus; dengue virus;

    Abstract : Background: A majority of the three million children in Africa that do not survive their fifth birthday die from infections that often start as a seemingly uncomplicated febrile illness. Primary health care workers frequently encounter febrile children with a negative malaria rapid diagnostic test (mRDT), in particular in places like Zanzibar with a considerable decline in malaria prevalence. READ MORE

  5. 5. Gestational Islet Autoimmunity, Infections, and Type 1 Diabetes

    Author : Maria Elfving; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gestation; Enterovirus infection; Pediatri; Pediatrics; Children; Type 1 diabetes; Islet autoantibodies;

    Abstract : The intention of this thesis was to investigate autoimmune markers for type 1 diabetes, together with signs of enterovirus infections during the pre- and perinatal period of life, and their possible association with the development of diabetes during childhood, adolescence, and young adulthood. We found that: 1. READ MORE