Search for dissertations about: "embryology human"
Showing result 1 - 5 of 10 swedish dissertations containing the words embryology human.
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1. Molecular specification of expanded forebrain neural stem and progenitor cells
Abstract : The molecular specification of neural precursor cells has been suggested to be a progressive process, with a transition from an early requirement for extrinsic signals to intrinsic mechanisms. Thus, the cells in the nervous system acquire distinct fates in response to extrinsic signals, which activate repertoires of transcription factors in a region and cell type specific manner. READ MORE
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2. Hypoxia and differentiation in human neuroblastoma cells
Abstract : The childhood tumour neuroblastoma is derived from immature cells of the sympathetic nervous system, which have become arrested at different maturation stages. Neuroblastoma is a malignancy with a high degree of heterogeneity, and there is a correlation between a poor differentiation status and a more aggressive phenotype. READ MORE
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3. Human Embryonic Stem Cells; A novel model system for early human development
Abstract : Human embryonic stem cells (HESC) have since their first description in 1998 been recognized as a theoretically endless source of cells capable of differentiation into any somatic cell type. Although great attention has been given to their potential use in cell- based therapy, they are equally important as research tools for studies on early human development, both normal and diseased. READ MORE
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4. Structural and evolutionary studies of a lipocalin: the alpha1-microglobulin protein and its gene
Abstract : a1-microglobulin is a small glycoprotein present in plasma and in tissues surrounding the gastrointestinal and respiratory tracts. a1-microglobulin is a member of the lipocalin protein family and exhibits several of the typical traits of a lipocalin; it binds an unknown ligand which causes the brown color of the protein, it forms complexes with various different proteins and there have been indications of the presence of a receptor for a1-microglobulin on T-lymphocytes. READ MORE
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5. Studies on chondrocyte integrins and mechanical signaling
Abstract : Integrins are a family of cell surface receptors known to bind matrix proteins and to mediate signals such as mechanical signals between the cell and the surrounding matrix. We have studied integrins that are expressed by chondrocytes, with specific focus on the integrins that interact with the cartilage matrix protein collagen type II. READ MORE
