Search for dissertations about: "enantiomer"

Showing result 1 - 5 of 80 swedish dissertations containing the word enantiomer.

  2. 1. Computational modelling of enzyme selectivity

    Author : Paul Bauer; Shina Caroline Lynn Kamerlin; Mikael Widersten; Kenneth Ruud; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; enantiomer; epoxide hydrolase; chiral catalysis; empirical valence bond approach; method development; Biokemi; Biochemistry;

    Abstract : Enantioselective reactions are one of the ways to produce pure chiral compounds. Understanding the basis of this selectivity makes it possible to guide enzyme design towards more efficient catalysts. READ MORE

  4. 2. Introducing weak affinity chromatography to drug discovery with focus on fragment screening

    Author : Minh-Dao Duong-Thi; Sten Ohlson; Brian Dymock; Linnéuniversitetet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; affinity LC-MS; fragment-based drug discovery; fragment screening; high throughput; mass spectrometry; stereoisomer; enantiomer; thrombin; weak affinity chromatography; WAC; WAC-MS.; Biomedical Sciences; Biomedicinsk vetenskap; Biokemi; Biochemistry;

    Abstract : Fragment-based drug discovery is an emerging process that has gained popularity in recent years. The process starts from small molecules called fragments. One major step in fragment-based drug discovery is fragment screening, which is a strategy to screen libraries of small molecules to find hits. READ MORE

  5. 3. New applications and developments of field-asymmetric ion mobility spectrometry - mass spectrometry (FAIMS-MS)

    Author : Axel Mie; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; triazine; enantiomer; ion focusing; ion mobility; FAIMS; DMS; axial ion inlet;

    Abstract : Field asymmetric ion mobility spectrometry (FAIMS), also commonly termed differential mobility spectrometry (DMS), is a gas-phase ion separation technology. FAIMS exploits differences in high-electric-field to low-electric-field ion mobility ratios to discriminate between ion species. READ MORE

  6. 4. Diastereomeric Effects in DNA Binding – Biological and Biophysical Studies on Ruthenium Complexes

    Author : Anna Mårtensson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neighbor interaction; spectroscopy; diastereomeric; kinetics; antimicrobial activity; ruthenium; calorimetry; intercalation; DNA; enantiomer;

    Abstract : Organic molecules, such as glucose and amino acids, are most often chiral. This means that their mirror-images are different, in the same way a left and a right hand are different from each other. For example, the DNA double helix in its standard form twists like a right-handed screw. READ MORE

  7. 5. Molecularly Imprinted Matrices for Electrochromatography

    Author : Leif Schweitz; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chemical technology and engineering; capillary electrophoresis; enantiomer; film coating; microparticle; continuous bed; monolith; molecular imprinting; capillary electrochromatography; Kemiteknik och kemisk teknologi; Analytical chemistry; Analytisk kemi;

    Abstract : This thesis deals with the combination of electrochromatography and molecular imprinting technology. Electrochromatography is characterised by high separation efficiency, simple instrumentation, and minute consumption of sample. READ MORE