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Showing result 1 - 5 of 80 swedish dissertations matching the above criteria.
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1. Computational modelling of enzyme selectivity
Abstract : Enantioselective reactions are one of the ways to produce pure chiral compounds. Understanding the basis of this selectivity makes it possible to guide enzyme design towards more efficient catalysts. READ MORE
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2. Introducing weak affinity chromatography to drug discovery with focus on fragment screening
Abstract : Fragment-based drug discovery is an emerging process that has gained popularity in recent years. The process starts from small molecules called fragments. One major step in fragment-based drug discovery is fragment screening, which is a strategy to screen libraries of small molecules to find hits. READ MORE
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3. New applications and developments of field-asymmetric ion mobility spectrometry - mass spectrometry (FAIMS-MS)
Abstract : Field asymmetric ion mobility spectrometry (FAIMS), also commonly termed differential mobility spectrometry (DMS), is a gas-phase ion separation technology. FAIMS exploits differences in high-electric-field to low-electric-field ion mobility ratios to discriminate between ion species. READ MORE
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4. Diastereomeric Effects in DNA Binding – Biological and Biophysical Studies on Ruthenium Complexes
Abstract : Organic molecules, such as glucose and amino acids, are most often chiral. This means that their mirror-images are different, in the same way a left and a right hand are different from each other. For example, the DNA double helix in its standard form twists like a right-handed screw. READ MORE
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5. Molecularly Imprinted Matrices for Electrochromatography
Abstract : This thesis deals with the combination of electrochromatography and molecular imprinting technology. Electrochromatography is characterised by high separation efficiency, simple instrumentation, and minute consumption of sample. READ MORE