Search for dissertations about: "end-stage renal disease"

Showing result 11 - 15 of 80 swedish dissertations containing the words end-stage renal disease.

2. 11. Molecular studies of complications in end stage renal disease : focus on expression and variations of candidate susceptibility genes

   Author : Alicia Bergsten; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : End stage renal disease (ESRD) is a complex multifactorial disorder, where both environmental and genetic factors are contributing to the phenotype. The most common complications seen in ESRD patients are malnutrition, inflammation and atherosclerosis and the coexistence of these complications is denoted the MIA syndrome, which is associated with inexplicably high mortality. READ MORE

4. 12. Prospective and longitudinal human studies of lead and cadmium exposure and the kidney

   Author : Johan Nilsson Sommar; Ingvar A Bergdahl; Max Petzold; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cadmium; end-stage renal disease; kidney; lead; longitudinal; matched case-control; mixed effects; prospective; Occupational and Environmental Medicine; arbets- och miljömedicin;

   Abstract : Cadmium and lead accumulate in humans and can have toxic effects. Exposure to cadmium is well known to cause kidney damage. Cadmium binds to metallothioneins, proteins that play a role in cadmium transport. READ MORE

5. 13. Effects of gastric bypass surgery in patients with obesity and type 2 diabetes

   Author : Vasileios Liakopoulos; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gastric bypass; bariatric surgery; obesity; type 2 diabetes mellitus; cardiovascular disease; mortality; risk factors; renal disease; adverse events;

   Abstract : Background: The effects of Roux-en-Y gastric bypass (GBP) have not been adequately explored in patients with concurrent obesity and type 2 diabetes mellitus (T2DM) to the same extent as has occurred for individuals with obesity alone. The overall aim of this thesis is to thoroughly examine the effects of GBP surgery in patients with obesity and T2DM in terms of cardiovascular disease and mortality, changes in various comorbidities, risk factors, and renal function as well as reporting adverse events. READ MORE

6. 14. Membranous Nephropathy - Challenges in diagnostics and treatment

   Author : Jennie Lönnbro-Widgren; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glomerulonephritis; Membranous nephropathy; Proteinuria; Phospholipase A2 receptor; Cancer; End-stage renal disease;

   Abstract : The variability in the pathogenesis, clinical presentation and outcome of membranous nephropathy (MN) poses major clinical challenges and raises different questions, both regarding diagnostics and treatment of patients with MN. The aims of this thesis were therefore to examine: 1) differences in the glomerular expression of different IgG subclasses and phospholipase A2 receptor (PLA2R) between patients with idiopathic and malignancy-associated MN; 2) treatment pattern of patients with idiopathic MN; and 3) if the serum PLA2R antibody level at diagnosis can be used as a prognostic marker. READ MORE

7. 15. Living with haemodialysis close to death - patients' and close relatives' experiences

   Author : Lena Axelsson; Birgitta Klang; Stefan Jacobson; Sissel Andreassen Gleissman; Carina Lundh Hagelin; Britt-Marie Ternestedt; Sophiahemmet Högskola; Karolinska Institutet; Karolinska Institutet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Close relative; Death; Dying; End of life; End-stage renal disease; haemodialysis; Palliative care; Phenomenological-hermeneutics; Qualitative content analysis; Retrospective interviews; Serial interviews; close relative;

   Abstract : The overall aim of this thesis is to generate  understanding and knowledge a bout the experiences of  patients living with haemodialysis, and their close relati ves, near the end of life. In studies I and II we  conducted a series of 31 qualitative interviews over a period of 12 months with 8 severely ill patients  (aged 66–87) treated with haemodialysis. READ MORE