Search for dissertations about: "endocannabinoid"
Showing result 1 - 5 of 18 swedish dissertations containing the word endocannabinoid.
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1. Endocannabinoid metabolism : the impact of inflammatory factors and pharmacological inhibitors
Abstract : The endocannabinoid (eCB) system is an endogenous signaling system consisting of ligands (referred to as endocannabinoids, eCBs), receptors and metabolic enzymes. The eCB system is involved in homeostatic control of a variety of biological functions such as neuronal signaling, mood, appetite and pathological conditions such as pain, inflammation and tumour progression. READ MORE
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2. The endocannabinoid system : a translational study from Achilles tendinosis to cyclooxygenase
Abstract : The endogenous cannabinoids anandamide (arachidonoyl ethanolamide, AEA) and 2-arachidonoyl glycerol (2-AG) exert their effect by activating cannabinoid receptors (CB). These receptors mediate a broad range of physiological functions such as beneficial effects in pain and inflammation, although little is known about the expression of CB receptors in human pain conditions. READ MORE
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3. The cellular processing of the endocannabinoid anandamide and its pharmacological manipulation
Abstract : Anandamide (arachidonoyl ethanolamide, AEA) and 2-arachidonoyl glycerol (2-AG) exert most of their actions by binding to cannabinoid receptors. The effects of the endocannabinoids are short-lived due to rapid cellular accumulation and metabolism, for AEA, primarily by the enzymes fatty acid amide hydrolase (FAAH). READ MORE
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4. Fatty acid amide hydrolase - A target for anti-inflammatory therapies?
Abstract : Anti-inflammatory drugs are a widely used class of therapeutic agents, but the use of non-steroidal anti-inflammatory drugs (NSAID) is hampered by their gastrointestinal side-effects. Recent reports that cyclooxygenase-2 inhibitors may cause cardiovascular events underline the importance of identifying new therapeutic strategies for the treatment of inflammation. READ MORE
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5. Endocannabinoids and N-acylethanolamines in translational pain research : from monoacylglycerol lipase to muscle pain
Abstract : In the early nineties cannabinoid receptors, the main target for Δ9-tetrahydrocannabinol (THC), the psychoactive component of marijuana were identified. Shortly after their endogenous ligands, N-arachidonoylethanolamine (anandamide, AEA) and 2-diacylglycerol (2-AG) were characterized. READ MORE