Search for dissertations about: "endocrine thesis"

Showing result 1 - 5 of 562 swedish dissertations containing the words endocrine thesis.

  2. 1. Genetic Aspects of Endocrine Tumorigenesis : A Hunt for the Endocrine Neoplasia Gene

    Author : Alberto Delgado Verdugo; Peyman Björklund; gunnar westin; Per Hellman; Filip Farnebo; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Exome sequencing; SDHAF2; epigenetics; methylation; methylation array; Sanger sequencing; pheochromocytoma; SI-NETs; carcinoid; oncology; endocrine surgery; parathyroid; Genetics; Genetik; Kirurgi; Surgery;

    Abstract : Endocrine tumors arise from endocrine glands. Most endocrine tumors are benign but malignant variants exist. Several endocrine neoplasms display loss of parts of chromosome 11 or 18, produce hormones and responds poorly to conventional chemotherapeutics. The multiple endocrine neoplasia syndromes are mainly confined to endocrine tumors. READ MORE

  4. 2. Pancreatic Endocrine Tumourigenesis : Genes of potential importance

    Author : Térèse A. Johansson; Barbro Eriksson; Britt Skogseid; Gunnar Westin; Martin Bäckdahl; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreatic endocrine tumour; Multiple endocrine neoplasia type 1; Tumourigenesis; Notch signalling; Notch1; Hes1; Neurog3; Neurod1; Men1; Ascl1; Pou3f4; Pdx1; Rpl10; Dlk1; Dkk1; Tph1; menin; Tumour biology; Tumörbiologi;

    Abstract : Understanding signalling pathways that control pancreatic endocrine tumour (PET) development and proliferation may reveal novel targets for therapeutic intervention. The pathogenesis for sporadic and hereditary PETs, apart from mutations of the MEN1 and VHL tumour suppressor genes, is still elusive. READ MORE

  5. 3. Adjuvant treatments to prevent local reurrence after breast-conserving surgery for early breast cancer : radiation, endocrine- or brachytherapy

    Author : Åsa Wickberg; Göran Liljegren; Johan Ahlgren; Roger Olofsson Bagge; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast-conserving surgery; radiotherapy; endocrine therapy; intraoperative brachytherapy;

    Abstract : Radiotherapy after breast-conserving surgery due to breast cancer is an established treatment, known to reduce the incidence of recurrence and even death from the disease. However some women are over-treated with sometimes serious adverse effects. De-escalating the treatment and find alternative adjuvant methods are becoming an important issue. READ MORE

  6. 4. Endocrine disruption in fish : Effects of 17α-ethinylestradiol exposure on non-reproductive behavior, fertility and brain and testis transcriptome

    Author : Tove Porseryd; Inger Porsch Hällström; Ioanna Katsiadaki; Södertörns högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; 17α-ethinylestradiol; endocrine disrupting chemical; fish; behavior; fertility; transcriptome; RNA sequencing; Environmental Studies; Miljövetenskapliga studier; Östersjö- och Östeuropaforskning; Baltic and East European studies;

    Abstract : Aquatic environments are the end recipient for most anthropogenic chemical pollutants. One common chemical pollutant found in the aquatic environment is 17α-ethinylestradiol (EE2), a synthetic estrogen used in contraceptive pills. READ MORE

  7. 5. Neurocognitive and endocrine dysfunction in women with exhaustion syndrome

    Author : Agneta Sandström; Tommy Olsson; Lars Nyberg; Marie Åsberg; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cognition; attention; working memory; exhaustion syndrome; major depression; cortisol; HPA-axis; proinflammatory cytokines; psychology; neurocognitive; endocrine; fMRI; MRI; prefrontal cortex; multivariate; women; personality; TCI; stress; Public health medicine research areas; Folkhälsomedicinska forskningsområden; Diagnostic radiology; Diagnostisk radiologi; medicin; Medicine; diagnostisk radiologi; Diagnostic Radiology;

    Abstract : Stress has emerged as one of the most important factors to consider in psychiatric diagnoses and has become a common reason for long-term sick leave (LTSL). Roughly 50% of LTSL due to psychiatric diseases are thought to be associated with work-related stress. READ MORE