Search for dissertations about: "endocrinology thesis"

Showing result 21 - 25 of 326 swedish dissertations containing the words endocrinology thesis.

  2. 21. Epidemiology of diabetes in a well defined population in Sweden: the Skaraborg Diabetes Registry

    Author : Bo Berger; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; diabetologi; Endokrinologi; diabetology; secreting systems; Endocrinology; Medicin människa och djur ; Medicine human and vertebrates ; IA-2A; GADA; ICA; islet antibodies; C-peptide; mortality; prevalence; serology; transplantation; Immunologi; serologi; Public health; incidence; epidemiology; epidemiologi; sekretion; Folkhälsa;

    Abstract : Time trends in prevalence, incidence and mortality was followed in 15000 diabetic patients in 1991?2005. Clinical findings, C-peptide protocols, and islet antibodies were compared in their ability to distinguish type 1 from type 2 diabetes, and factors associated with the prognosis of diabetes were explored. READ MORE

  4. 22. The bank vole (Myodes glareolus) – a novel animal model for the study of diabetes mellitus

    Author : Martin Blixt; Stellan Sandler; Johnny Ludvigsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bank vole; pancreatic islets; diabetes mellitus; hydropic degeneration; proinflammatory cytokine; Diabetology; Diabetologi; Endocrinology; Endokrinologi; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : The bank vole (Microtus arvalis) develops glucose intolerance both when kept in captivity and in the wild state. Glucose intolerant bank voles kept in captivity exhibited polydipsia, polyuria, hyperglycemia, hyperinsulinemia, islet autoantibodies and a markedly changed islet structure resembling so–called hydropic degeneration. READ MORE

  5. 23. Common variants in genes regulating free fatty acid metabolism and risk of type 2 diabetes and cardiovascular disease

    Author : Martin Carlsson; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cardiovascular disease; free fatty acids; genetics; UCP1; beta3-adrenergic receptor; beta2-adrenergic receptor; type 2 diabetes mellitus; FABP2; stroke; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Abstract : Abstract The present study evaluated genetic and metabolic factors influencing the risk for type 2 diabetes and cardiovascular disease (CVD) with special reference to increased concentrations of free fatty acids (FFA) in 1174 Swedish diabetic and nondiabetic subjects. Common polymorphisms in the fatty acid binding protein 2 (FABP2), the B2-adrenergic receptor (B2-AR), the B3 -adrenergic receptor (B3-AR) and the uncoupling protein 1 (UCP-1) genes were related to anthropometric and metabolic variables. READ MORE

  6. 24. Heritability of blood pressure: monogenes and polygenes

    Author : Cristiano Fava; diabetes och endokrinologi Genomik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; Biomedicinska vetenskaper; Biomedical sciences; kidney; Adducin-1; CLC-kb; Gitelman syndrome; association; heritabilty; genetics; hypertension; Blood pressure; blood pressure variability; Medicin människa och djur ; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Abstract : High blood pressure (BP) is associated with cardiovascular morbidity and mortality. Both genetic and environmental factors are implicated in BP homeostatsis and hypertension development. READ MORE

  7. 25. Identification of abnormally expressed genes in skeletal muscle contributing to insulin resistance and type 2 diabetes

    Author : Xudong Huang; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrinology; secreting systems; diabetology; Endokrinologi; gene expression; high-fat intake; RT-PCR; mitochondrial genes; cathepsin L; Shc; IRS-2; IRS-1; GS; cDNA differential display; Insulin resistance; type 2 diabetes; sekretion; diabetologi;

    Abstract : The metabolic defects of insulin resistance and type 2 diabetes can result from changes in gene expression and protein functions due to genetic and environmental influences. The aim of this study was to identify abnormally expressed genes associated with insulin resistance or type 2 diabetes, and further to test whether possible defects are inherited or acquired. READ MORE